55661-08-0

Usage

Uses

Used in Pharmaceutical Industry:
4-Methoxy-2,6-dimethylbenzenesulfonyl chloride is used as a reagent for the synthesis of pharmaceuticals. Its unique structure allows it to be a key component in the creation of various medicinal compounds, contributing to the development of new drugs and therapies.
Used in Agrochemical Industry:
In the agrochemical sector, 4-Methoxy-2,6-dimethylbenzenesulfonyl chloride is employed as a building block in the synthesis of agrochemicals. Its properties make it suitable for the development of compounds used in crop protection and other agricultural applications.
Used in Synthesis of Functional Materials:
4-Methoxy-2,6-dimethylbenzenesulfonyl chloride is utilized as a precursor in the synthesis of functional materials. Its chemical properties enable the production of materials with specific characteristics, useful in various industrial applications.
Used as a Building Block in Sulfamide Synthesis:
4-Methoxy-2,6-dimethylbenzenesulfonyl chloride is used as a building block in the synthesis of other sulfonamides, which are important in medicinal chemistry. Its presence in these molecules can enhance their therapeutic properties and contribute to the advancement of pharmaceutical research.
Used as a Protecting Group in Organic Synthesis:
4-Methoxy-2,6-dimethylbenzenesulfonyl chloride serves as a protecting group for alcohols and amines in organic synthesis. Its ability to temporarily mask functional groups allows for selective reactions to occur, facilitating complex organic synthesis processes.

InChI:InChI=1/C9H11ClO3S/c1-6-4-8(13-3)5-7(2)9(6)14(10,11)12/h4-5H,1-3H3

Upstream product

• 7790-94-5 chlorosulfonic acid 
• 874-63-5 3,5-dimethylmethoxybenzene 

Downstream Products

• 279256-29-0 tert-butyl 2(R)-(2,6-dimethyl-4-methoxybenzene sulfonylamino)-3-phthalimido-propionate 
• 1018826-75-9 (1-(4-methoxy-2,6-dimethylphenylsulfonyl)-1,2,3,4-tetrahydroquinolin-2-yl)methanol 
• 1018826-56-6 perfluorophenyl 4-methoxy-2,6-dimethylbenzenesulfonate 
• 1174284-27-5 N-benzyl-N-(2-hydroxyethyl)-4-methoxy-2,6-dimethylbenzenesulfonamide 
• 1226949-53-6 (S)-1-(3-(1-(4-Methoxy-2,6-dimethylphenylsulfonyl)pyrrolidin-2-yl)propylsulfonyl)-4-(1-methylpiperidin-4-yl)piperazine 
• 1246506-32-0 3-[[(4-methoxy-2,6-dimethyl-phenyl)sulfonyl]amino]-2,3-dihydro-1H-indene-5-carboxylic acid methyl ester 
• 1072354-75-6 {(2S)-1-[(4-methoxy-2,6-dimethylphenyl)sulfonyl]piperidin-2-yl}methanol 
• 1119282-87-9 2-{2-[(4-methoxy-2,6-dimethylbenzenesulphonyl)methylamino]ethoxy}-N-methyl-N-[(1R,3S)-3-(4-methylpiperazin-1-yl)cyclohexyl]acetamide 
• 1119282-90-4 2-{2-[(4-methoxy-2,6-dimethylbenzenesulphonyl)methylamino]ethoxy}-N-methyl-N-[(1S,3R)-3-(4-methylpiperazin-1-yl)cyclohexyl]acetamide 
• 1240308-11-5 {2-[(4-methoxy-2,6-dimethylbenzenesulphonyl)methylamino]ethoxy}acetic acid sodium salt 

Relevant academic research and scientific papers

Intermolecular 1,2-Difunctionalization of Alkenes Enabled by Fluoroamide-Directed Remote Benzyl C(sp3)-H Functionalization

A copper-catalyzed remote benzylic C-H functionalization strategy enabling 1,2-difunctionalization of alkenes with 2-methylbenzeneamides and nucleophiles, including alcohols, indoles, pyrroles, and the intrinsic amino groups, is reported, which is charact

ACID ADDITION SALTS OF THE 2-[2-[[(4-METHOXY-2,6-DIMETHYLPHENYL)SULFONYL]-(METHYL)AMINO]ETHOXY]-N-METHYL-N-[3-(4-METHYLPIPERAZIN-1-YL)CYCLOHEXYL] ACETAMIDE AND THE USE THEREOF AS BRADYKININ B1 RECEPTORANTAGONISTS

The present invention relates to the new acid addition salts AB of the following free base of formula A or the enantiomer thereof with a physiologically acceptable acid B which is selected from among hydrochloric acid, fumaric acid and tartaric acid, as well as the polymorphs, hydrates and solvates thereof.

NEW COMPOUNDS

Novel compounds of which the following is exemplary:

Substituted Pyrimidine and Triazine Compounds

Substituted pyrimidine and triazine compounds corresponding to formula I wherein R1, R2, R3, R4a, R4b, R5a, R5b, R7, R8, R9a, R9b, R10, R11, A, a, b, s, t, V, W1, W2 and W3 have defined meanings, pharmaceutical compositions comprising such compounds, a process for preparing such compounds, and the use of such compounds and compositions to treat or inhibit pain and/or other disorders or disease states.

Substituted Indole Compounds

Substituted indole compounds corresponding to the formula I: In which R8, R9a, R9b, R10, R11, R200, R210, A, D, T, q, s and t have defined meanings, processes for the preparation thereof, pharmaceutical compositions containing such compounds and the use of substituted indole compounds for the treatment or inhibition of pain and other conditions which are at least partly mediated by Bradykinin 1 receptors (B1R).

Substituted Spiroamide Compounds

Substituted spiroamide compounds corresponding to formula (I): wherein A, B, Q1, Q2, Q3, Q4, R1, R8, R9a, R9b, R12, R13, R200 and R210 have defined meanings, processes for their preparation, pharmaceutical compositions containing such compounds, and the use of such compounds for treating or inhibiting pain or other conditions mediated at least in part by the bradykinin 1 receptor (B1R).

Substituted Spiroamine Compounds

Substituted spiroamine compounds corresponding to the formula (I) In which m, n, o, p, Q, r, s, t, R1, R2, R3, R4a, R4b, R5a, R5b, R6a, R6b, R7, R8, R9, R10 and R11 have defined meanings; a process for the preparation of such compounds, pharmaceutical compositions containing such compounds and the use of substituted spiroamines for the treatment or inhibition of pain and/or other conditions mediated by the bradykinin 1 receptor.

SULFONYLATED TETRAHYDROAZOLOPYRAZINES AND THEIR USE AS MEDICINAL PRODUCTS

The present invention relates to sulfonylated tetrahydroazolopyrazines, methods for the preparation thereof, medicinal products containing these compounds and the use of substituted indole compounds for the preparation of medicinal products (Formula I).

Substituted Disulfonamide Compounds

Substituted disulfonamide compounds corresponding to formula I: In which R1, R2, R3, R4a, R4b, R5a, R5b, R8, R9a, R9b, R10, R11, a, b, s, t and A have defined meanings, pharmaceutical compositions containing one or more such compounds, processes for preparing such compounds, and a method of using such compounds for the treatment or inhibition of pain and/or other conditions mediated by the bradykinin receptor 1 (BR1).