55661-08-0

Basic information

• Product Name: 4-Methoxy-2,6-dimethylbenzenesulfonyl chloride
• Synonyms: 4-methoxy-2,6-dimethyl-benzensulfonyl;4-methoxy-2,6-dimethyl-benzenesulfonyl chloride;2,6-Dimethyl-4-methoxybenzenesulfonyl chloride;2,6-Dimethyl-4-methoxyphenylsulfonyl chloride;4-Methoxy-2,6-xylenesulfonyl chloride;4-Methoxy-2,6-diMethylbenzene-1-sulfonyl chloride;4-(Chlorosulphonyl)-3,5-dimethylanisole, 2-(Chlorosulphonyl)-5-methoxy-m-xylene;5-methoxy-2,3-dimethylbenzene-1-sulfonyl chloride
• CAS NO: 55661-08-0
• Molecular Formula: C₉H₁₁ClO₃S
• Molecular Weight: 234.7
• Mol File: 55661-08-0.mol
• Article Data: 21

Chemical Properties

• Boiling Point: 356.097 °C at 760 mmHg
• Flash Point: 169.162 °C
• Appearance: /
• Density: 1.285
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.525
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• CAS DataBase Reference: 4-Methoxy-2,6-dimethylbenzenesulfonyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Methoxy-2,6-dimethylbenzenesulfonyl chloride(55661-08-0)
• EPA Substance Registry System: 4-Methoxy-2,6-dimethylbenzenesulfonyl chloride(55661-08-0)

Safety Data

• Hazardous Substances Data: 55661-08-0(Hazardous Substances Data)

Usage

General Description

4-Methoxy-2,6-dimethylbenzenesulfonyl chloride is a chemical compound with the molecular formula C9H11ClO3S. It is a sulfonyl chloride derivative, meaning it contains a sulfur atom bonded to two oxygen atoms and a chlorine atom. 4-Methoxy-2,6-dimethylbenzenesulfonyl chloride is commonly used as a reagent in organic chemistry for the synthesis of various pharmaceuticals, agrochemicals, and functional materials. It is also used as a building block in the synthesis of other sulfonamides, which are important in medicinal chemistry. Additionally, it can be used as a protecting group for alcohols and amines in organic synthesis. Its properties and versatile reactivity make it a valuable chemical in the pharmaceutical and chemical industries.

InChI:InChI=1/C9H11ClO3S/c1-6-4-8(13-3)5-7(2)9(6)14(10,11)12/h4-5H,1-3H3

Upstream product

• 874-63-5 3,5-dimethylmethoxybenzene 
• 7790-94-5 chlorosulfonic acid 

Downstream Products

• 75813-41-1 N^α-benzyloxycarbonyl-N^G-(4-methoxy-2,6-dimethylbenzenesulphonyl)arginine 
• 766558-31-0 N-(2-hydroxyethyl)-4-methoxy-2,6,N-trimethylbenzenesulphonamide 
• 279256-29-0 tert-butyl 2(R)-(2,6-dimethyl-4-methoxybenzene sulfonylamino)-3-phthalimido-propionate 
• 1018826-75-9 (1-(4-methoxy-2,6-dimethylphenylsulfonyl)-1,2,3,4-tetrahydroquinolin-2-yl)methanol 
• 1018826-56-6 perfluorophenyl 4-methoxy-2,6-dimethylbenzenesulfonate 
• 1174284-27-5 N-benzyl-N-(2-hydroxyethyl)-4-methoxy-2,6-dimethylbenzenesulfonamide 
• 1021373-55-6 [1-(4-methoxy-2,6-dimethyl-phenylsulfonyl)-piperidin-2-yl]-methanol 
• 1174068-38-2 ethyl 3-(1-(4-methoxy-2,6-dimethylphenylsulfonyl)piperidin-2-yl)propanoate 
• 1174068-39-3 C₂₀H₃₁NO₅S 
• 1224586-54-2 Methyl 1-(4-methoxy-2,6-dimethylphenylsulfonamido)cyclobutane-carboxylate 
• 1007869-39-7 C₁₄H₂₁NO₅S 
• 1007870-86-1 C₁₃H₁₉NO₅S 
• 1239952-73-8 methyl 2-(4-methoxy-2,6-dimethylphenylsulfonyl)-1,2,3,4-tetrahydroisoquinoline-7-carboxylate 
• 1239953-15-1 methyl 7-(4-methoxy-2,6-dimethylphenylsulfonyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine-1-carboxylate 

Relevant articles and documents

Intermolecular 1,2-Difunctionalization of Alkenes Enabled by Fluoroamide-Directed Remote Benzyl C(sp3)-H Functionalization

A copper-catalyzed remote benzylic C-H functionalization strategy enabling 1,2-difunctionalization of alkenes with 2-methylbenzeneamides and nucleophiles, including alcohols, indoles, pyrroles, and the intrinsic amino groups, is reported, which is charact

COMPOUNDS

Novel compounds, with the following being exemplary:

Substituted Pyrimidine and Triazine Compounds

Substituted pyrimidine and triazine compounds corresponding to formula I wherein R1, R2, R3, R4a, R4b, R5a, R5b, R7, R8, R9a, R9b, R10, R11, A, a, b, s, t, V, W1, W2 and W3 have defined meanings, pharmaceutical compositions comprising such compounds, a process for preparing such compounds, and the use of such compounds and compositions to treat or inhibit pain and/or other disorders or disease states.