109911-47-9Relevant academic research and scientific papers
Carbamoyl Fluoride-Enabled Enantioselective Ni-Catalyzed Carbocarbamoylation of Unactivated Alkenes
Li, Yue,Luan, Yu-Xin,Qi, Shao-Long,Wang, Rong-Hua,Ye, Mengchun,Zhang, Feng-Ping
supporting information, p. 19844 - 19849 (2021/01/01)
A carbamoyl fluoride-enabled enantioselective Ni-catalyzed carbocarbamoylation of unactivated alkenes was developed, providing a broad range of chiral γ-lactams bearing an all-carbon quaternary center in 45-96% yield and 38-97% ee.
New applications of dithiocarbamates in organic synthesis
Grainger, Richard S.,Innocenti, Paolo
, p. 568 - 571 (2008/02/08)
The application of dithiocarbamates in group transfer radical cyclization reactions is described. Carbamoyl diethyldithiocarbamates are synthesized in two high-yielding steps from secondary amines and act as sources of carbamoyl radicals through chemical
Generation and cyclization of unsaturated carbamoyl radicals derived from S-4-pentynyl carbamothioates under tin-free conditions
Benati, Luisa,Bencivenni, Giorgio,Leardini, Rino,Minozzi, Matteo,Nanni, Daniele,Scialpi, Rosanna,Spagnolo, Piero,Zanardi, Giuseppe
, p. 3192 - 3197 (2007/10/03)
The radical reaction of benzenethiol with S-4-pentynyl carbamothioates provides a valuable protocol for the tin-free generation of carbamoyl radicals, which arise from intramolecular substitution at sulfur by the initial sulfanylvinyl radicals. This procedure can be usefully employed to achieve N-benzylcarbamoyl radical 5-exo and 4-exo cyclizations leading, respectively, to pyrrolidinones and azetidinones, although, for the latter, it seems of lesser utility. Novel evidence is presented that. N-tosyl-substituted carbamoyl radicals display a peculiar tendency to yield the corresponding isocyanate by β-elimination of the tosyl radical.
Dithiocarbamate group transfer cyclization reactions of carbamoyl radicals under "tin-free" conditions
Grainger, Richard S.,Innocenti, Paolo
, p. 3445 - 3448 (2007/10/03)
Oxygen or nitrogen? Radical chemists overwhelmingly choose to work with xanthates rather than dithiocarbamates, yet the latter offer a distinct advantage in the case of a new method for generating carbamoyl radicals. Functionalized lactams of various ring
Palladium-Catalysed Synthesis of α-Methylene γ-Butyrolactams via Cyclisation of Homoallylic Chloroformamides
Henin, Francoise,Muzart, Jacques,Pete, Jean-Pierre
, p. 6339 - 6340 (2007/10/02)
3-Methylene 2-pyrrolidinones were prepared by intramolecular cyclisation of homoallylic chloroformamides catalysed by PdII or Pdo complexes.
