109913-40-8

Basic information

• Product Name: 3H-1,2,4-Triazol-3-one, 2-(2-chlorophenyl)-2,4-dihydro-5-methyl-
• CAS NO: 109913-40-8
• Molecular Formula: C9H8ClN3O
• Molecular Weight: 209.635
• Mol File: 109913-40-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 3H-1,2,4-Triazol-3-one, 2-(2-chlorophenyl)-2,4-dihydro-5-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 3H-1,2,4-Triazol-3-one, 2-(2-chlorophenyl)-2,4-dihydro-5-methyl-(109913-40-8)
• EPA Substance Registry System: 3H-1,2,4-Triazol-3-one, 2-(2-chlorophenyl)-2,4-dihydro-5-methyl-(109913-40-8)

Safety Data

• Hazardous Substances Data: 109913-40-8(Hazardous Substances Data)

Upstream product

• 108-90-7 chlorobenzene 
• 1445-45-0 Trimethyl orthoacetate 
• 590-28-3 potassium cyanate 
• 41052-75-9 o-chlorophenylhydrazine hydrochloride 
• 114648-64-5 acetone-(2-chloro-phenylhydrazone) 
• 133902-77-9 4-acetyl-1-(2-chlorophenyl)-3,3-dimethyl-1,2,4-triazolidin-5-one 
• 10449-07-7 (2-chlorophenyl)hydrazine 
• 95-51-2 o-chloroaniline 

Downstream Products

• 111992-16-6 4,5-dihydro-3-methyl-4-difluoromethyl-1-(2,4-dichlorophenyl)-1,2,4-triazol-5(1H)-one 
• 111992-17-7 4,5-dihydro-3-methyl-4-difluoromethyl-1-(2,4-dichloro-5-nitrophenyl)-1,2,4-triazole-5(1H)-one 
• 111992-18-8 2-(5-amino-2,4-dichlorophenyl)-4-(difluoromethyl)-2,4-dihydro-5-methyl-3H-1,2,4-triazol-3-one 
• 122836-35-5 sulfentrazone 

Relevant articles and documents

Synthesis method of metolachlor intermediate

The synthesis method comprises the following steps: S1) nitration reaction of chlorobenzene in a nitration reagent to obtain a mixture of o-chloronitrobenzene and p-chloronitrobenzene without separation. S2) The mixture of o-chloronitrobenzene and p-chloronitrobenzene is subjected to catalytic hydrogenation reaction to obtain the mixture of o-chloroaniline and p-chloroaniline, and the product does not need to be separated. S3) The mixture of o-chloroaniline and chloroaniline is subjected to diazotization reaction to obtain the mixture of o-chlorophenylhydrazine and p-chlorophenylhydrazine, and the product does not need to be separated. S4) The mixture of o-chlorophenylhydrazine and p-chlorophenylhydrazine and aldehyde are subjected to a condensation reaction to obtain a triazole ring mixture of Formulae I through a and I through b. S5) The triazole ring mixture is subjected to chlorination reaction to obtain the metolachlor intermediate shown in the formula I. 2, 4 - Dichloroaniline is used as a raw material, the production cost of the metolachlor is reduced, and the supply limitation of the raw material is avoided.

Method for synthesizing Sulfentrazone

The invention relates to a method for synthesizing Sulfentrazone. The method is characterized by comprising the steps of liberating o-chlorophenylhydrazine from o-chlorophenylhydrazine hydrochloride, which serves as a raw material, by an alkali, subjecting o-chlorophenylhydrazine to a reaction with trimethyl orthoacetate and potassium cyanate so as to obtain 1-o-chlorophenyl-3-methyl-1H-1,2,4-triazol-5-one, and then, subjecting 1-o-chlorophenyl-3-methyl-1H-1,2,4-triazol-5-one to N-alkylation, chlorination, nitration, reduction and sulfonylation, thereby obtaining the Sulfentrazone, wherein a composite catalyst and a solvent, i.e., dichloroethane are adopted in a chlorination reaction. The method for synthesizing the Sulfentrazone, disclosed by the invention, has the advantages that the o-chlorophenylhydrazine hydrochloride serves as the raw material, so that the steric hindrance of an intermediate product can be low, and the yield of the product is increased; and meanwhile, in the chlorination reaction, the composite catalyst is adopted, thus, the orientation effect on all atoms is good, and the solvent is dichloroethane, so that the recycling of the solvent is facilitated.