109923-78-6

Basic information

• Product Name: 6-N-benzoyl-2',3',5'-tri-O-benzoyl-β-L-adenosine
• Synonyms: 6-N-benzoyl-2',3',5'-tri-O-benzoyl-β-L-adenosine
• CAS NO: 109923-78-6
• Molecular Weight: 683.677
• Mol File: 109923-78-6.mol

Chemical Properties

• CAS DataBase Reference: 6-N-benzoyl-2',3',5'-tri-O-benzoyl-β-L-adenosine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-N-benzoyl-2',3',5'-tri-O-benzoyl-β-L-adenosine(109923-78-6)
• EPA Substance Registry System: 6-N-benzoyl-2',3',5'-tri-O-benzoyl-β-L-adenosine(109923-78-6)

Safety Data

• Hazardous Substances Data: 109923-78-6(Hazardous Substances Data)

Upstream product

• 3080-30-6 1-O-acetyl-2,3,5-tri-O-benzoyl-β-L-ribofuranose 
• 18055-47-5 N-Benzoyl-N,9-bis(trimethylsilyl)adenin 
• 98-88-4 benzoyl chloride 
• 5536-17-4 arabinosyl adenine 
• 4005-49-6 N-benzoyladenine 
• 66224-66-6 adenine 
• 20074-49-1 β-L-arabinofuranoside 
• 93-97-0 benzoic acid anhydride 
• 41546-19-4 α-L-lyxose 
• 171866-28-7 1-O-methyl-2,3,5-tri-O-benzoyl-L-ribofuranose 

Downstream Products

• 82144-96-5 5'-O-dimethoxytrityl-N,2'-O-dibenzoylarabinosyladenine 
• 82144-95-4 Benzoic acid (2R,3R,4S,5R)-5-(6-benzoylamino-purin-9-yl)-4-[(4-methoxy-phenyl)-diphenyl-methoxy]-2-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-tetrahydro-furan-3-yl ester 
• 82144-94-3 N,2'-O-dibenzoyl-3',5'-O-bis-monomethoxytrityl arabinosyladenine 
• 82144-93-2 N⁶-benzoyl-9-<2,5-di-O-(4-monomethoxytrityl)-β-D-arabinofuranosyl>adenine 
• 82144-92-1 N-benzoyl-3',5'-O-bis-monomethoxytritylarabinosyladenine 
• 93488-74-5 Benzoic acid (2R,3S,4R,5R)-2-(6-benzoylamino-purin-9-yl)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-3-yl ester 
• 79896-97-2 N6-benzoyl-9-β-D-arabinofuranosyladenine 
• 109923-79-7 3',5'-O-(1,1,3,3-tetraisopropyldisiloxanylidene)-N⁶-benzoyl-L-adenosine 
• 58-61-7 L-adenosine 
• 868663-26-7 N⁶-benzoyl-β-L-adenosine 

Relevant articles and documents

L-ribonucileosides for racemic RNA

Two L-ribosyl donors were synthesised from L-xylose, then submitted to a glycosidation reaction according to Vorbruggen's conditions to furnish L- ribonucleosides in high yield.

L-Ribonucleosides from L-xylose

L-Xylose was converted into a L-ribose derivative via an oxidation/reduction procedure. The L-ribosyl donor was submitted to a glycosidation reaction according to Vorbruggen's conditions to give L- ribonucleosides (L-uridine, L-cytidine, L-adenosine and L-guanosine) in high yield.

Chirally-modified oligonucleotides and the control of gene expression. The case of L-DNAs and -RNAs

The affinity of L-DNAs, L-RNAs and LD-DNAs for homopurine · homopyrimidine d.s. D-DNA and s.s. D-RNA was probed by gel electrophoresis and CD spectroscopy. It was found that the L-modified oligomers do not bind to d.s. DNA and to natural RNA that contains all four natural bases. Thus they cannot be used, in general, for the control of gene expression according to the antigene and antisense methodologies. Heterochiral complexes with 1:1 stoichiometry and low hem stability are formed, instead, by homopurinic L- RNA or L/D-DNA and homopyrimidinic L-RNA with the W/C complementary natural RNA sequences.

Synthesis of the mirror image of the RNA fragment D-CAAGG: A model compound to study interactions between oligonucleotides of opposite handedness

The pentamer L-CAAGG was prepared starting from properly protected β-L-ribonucleosides via a phosphotriester approach.The identity and chiral purity of the pentamer were established by 1H NMR and CD spectroscopy, respectively.