110-25-8Relevant articles and documents
PRODUCTION PROCESS FOR N-ACYLAMINO ACID
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Paragraph 0028, (2017/06/09)
PROBLEM TO BE SOLVED: To provide a production process in which a high-purity N-acylamino acid having a good color tone can be produced with high yield. SOLUTION: A production process for N-acylamino acid is provided in which an acylation reaction between an amino acid represented by formula (1) and a fatty acid chloride having a carbon number of 16 to 22 is performed in a mixed solvent between a water and an organic solvent and having an octanol/water partition coefficient of 1.6 to 3.5 under an alkali condition. (In the formula (1), R1 represents a hydrogen atom or a methyl group, R2 represents a hydrogen atom or an alkali metal atom, and n represents an integer of 1 or 2.). SELECTED DRAWING: None COPYRIGHT: (C)2017,JPOandINPIT
Preparation of alkali metal acyl amino acids
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, (2008/06/13)
A process of preparing alkali metal N-acyl amino acids, especially sodium N-acyl sarcosinates. The process of the invention eliminates the use of phosphorus trichloride or thionyl chloride and carboxylic acid chlorides. The process involves reacting the alkali metal N-acyl amino acid directly with a fatty acid at elevated temperatures with constant removal of water generated in the reaction.