1100-14-7Relevant academic research and scientific papers
Isoflavanones from the heartwood of Swartzia polyphylla and their antibacterial activity against cariogenic bacteria
Osawa,Yasuda,Maruyama,Morita,Takeya,Itokawa
, p. 2970 - 2974 (1992)
The methanolic extract of Swartzia polyphylla DC. heartwood had antibacterial activity against cariogenic bacteria, the mutans Streptococci. The chromatographic purification of the extract afforded seven flavonoids. Among them, three known isoflavanones, dihydrobiochanin A, ferreirin and darbergioidin, and one new isoflavanone, 5,2',4'-trihydroxy-7-methoxyisoflavanone (dihydrocajanin) had potent antibacterial activity against cariogenic bacteria. This effect was not detected on isoflavone derivatives. A comparative antibacterial study of various flavonoids was further performed, and their structure-activity relationship was discussed.
Organolead-mediated Arylation of Allyl β-Ketoesters: A Selective Synthesis of Isoflavanones and Isoflavones
Donnelly, Dervilla M.,Finet, Jean-Pierre,Rattigan, Bernard A.
, p. 1729 - 1736 (2007/10/02)
Arylation of A-ring substituted and unsabstituted 3-allyloxycarbonylchroman-4-ones with aryllead(IV) triacetates followed by selective catalytic deallyloxycarbonylation affords isoflavanones or isoflavones in high overall yields.The highest yield in the arylation step was observed in the reaction of 5,7-dimethoxychroman-4-one with the more hindered 2,4,6-trimethoxyphenyllead triacetate.
CATALYTIC TRANSFER HYDROGENATION, A CHEMO-SELECTIVE REDUCTION OF ISOFLAVONES TO ISOFLAVANONES
Krishnamurty, H.G.,Sathyanarayana, S.
, p. 1657 - 1664 (2007/10/02)
Isoflavones can be selectively reduced by catalytic transfer hydrogenation employing formic acid, ammonium formate or triethylammonium formate in the presence of 10percent Pd/C.The reaction is simple, clean and gives fair yields of isoflavanones.
