1100-15-8Relevant academic research and scientific papers
Total synthesis of apios isoflavones and investigation of their tyrosinase inhibitory activity
Asebi, Nana,Nihei, Ken-ichi
, (2019)
Apios isoflavone glucosides 1 and 2 were synthesized for the first time via Friedel–Crafts reaction, Bischler–Napieralski-type cyclization, and phase-transfer catalyzed glycosylation as the key steps. In addition, aglycones 4 and 5 and related natural iso
Constrained phytoestrogens and analogues as ERβ selective ligands
Miller, Chris P.,Collini, Michael D.,Harris, Heather A.
, p. 2399 - 2403 (2003)
A new series of ERbeta (ERβ) selective ligands has been prepared. One of the compounds 6, structurally related to the phytoestrogen apigenin 4, displays a binding preference for ERβ over ERα of over 40-fold. In addition to its binding selectivity, 6 was a
Substituted 10,11-benzo[b]fluoren-10-ones as estrogenic agents
-
, (2008/06/13)
This invention provides estrogen receptor modulators of formula 1, having the structure wherein X, Y1, Y2, Y3, Y4, Z1, Z2, Z3, and Z4 are as defined in the specificati
Organolead-mediated Arylation of Allyl β-Ketoesters: A Selective Synthesis of Isoflavanones and Isoflavones
Donnelly, Dervilla M.,Finet, Jean-Pierre,Rattigan, Bernard A.
, p. 1729 - 1736 (2007/10/02)
Arylation of A-ring substituted and unsabstituted 3-allyloxycarbonylchroman-4-ones with aryllead(IV) triacetates followed by selective catalytic deallyloxycarbonylation affords isoflavanones or isoflavones in high overall yields.The highest yield in the arylation step was observed in the reaction of 5,7-dimethoxychroman-4-one with the more hindered 2,4,6-trimethoxyphenyllead triacetate.
New 5-O-Methylisoflavones in the Roots of Yellow Lupin (Lupinus luteus L. cv. Barpine)
Tahara, Satoshi,Hashidoko, Yasuyuki,Ingham, John L.,Mizutani, Junya
, p. 1809 - 1820 (2007/10/02)
In addition to 5-O-methylgenistein (1), a further investigation of the isoflavonoid constituents in roots of the yellow lupin (Lupinus luteus L. cv.Barpine) has yielded five new 5-O-methylisoflavones named barpisoflavone A (2), 5-O-methyl-lupiwighteone (3
