1101181-68-3Relevant academic research and scientific papers
Bis(benzoyloxybenzyl)-DiPPro nucleoside diphosphates of anti-HIV active nucleoside analogues
Weinschenk, Lina,Gollnest, Tristan,Schols, Dominique,Balzarini, Jan,Meier, Chris
, p. 891 - 900 (2015/05/05)
Nucleoside analogues are extensively used as antiviral and anticancer agents. Their efficiency is dependent on their metabolism into the ultimately active nucleoside triphosphates. Often one step or even more in the metabolism of the nucleoside to the tri
Bioreversible protection of nucleoside diphosphates
Jessen, Henning Jacob,Schulz, Tilmann,Balzarini, Jan,Meier, Chris
supporting information; experimental part, p. 8719 - 8722 (2009/05/15)
(Figure Presented) Going incognito: A new prodrug approach has been developed to facilitate the diffusion of highly polar polyphosphorylated nucleosides across cell membranes (see scheme). Inside the cell, the masking groups on the nucleoside diphosphate
