110178-52-4

Basic information

• Product Name: 6-methyl-5-phenyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinoline
• Synonyms: 6-methyl-5-phenyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinoline
• CAS NO: 110178-52-4
• Molecular Weight: 267.327
• Mol File: 110178-52-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 6-methyl-5-phenyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 6-methyl-5-phenyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinoline(110178-52-4)
• EPA Substance Registry System: 6-methyl-5-phenyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinoline(110178-52-4)

Safety Data

• Hazardous Substances Data: 110178-52-4(Hazardous Substances Data)

Upstream product

• 6592-85-4 hydrastinine 
• 494-55-3 N-methyl-6,7-methylenedioxy-1,2,3,4-tetrahydroisoquinoline 
• 108-90-7 chlorobenzene 
• 1484-85-1 3,4-methylenedioxyphenylethylamine 
• 55507-12-5 5-phenyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinoline 
• 74-88-4 methyl iodide 
• 100-52-7 benzaldehyde 

Downstream Products

• 109721-48-4 6-methyl-5-phenyl-[1,3]dioxolo[4,5-g]isoquinolinium; iodide 

Relevant articles and documents

Nucleophilic addition of Lewis acid complexed α-amino carbanions to arynes: Synthesis of 1-aryl- N -methyl-1,2,3,4-tetrahydroisoquinolines

The direct C-1 arylation of N-methyl-1,2,3,4-tetrahydroisoquinolines via coupling of α-amino carbanions derived from Lewis acid complexed tetrahydroisoquinolines and in situ generated arynes is described. This process provides an easy access to the title compounds and a new synthetic route to (±)-cryptostyline alkaloids. Georg Thieme Verlag Stuttgart New York.