110271-41-5Relevant articles and documents
Synthesis of two naphthoquinone antibiotics pentalongin and psychorubrin
Kesteleyn, Bart,De Kimpe, Norbert,Van Puyvelde, Luc
, p. 1881 - 1883 (1999)
The synthesis of two naturally occurring pyranonaphthoquinone antibiotics, pentalongin (1) and psychombrin (2), is reported.
Synthesis of pyranonaphthoquinone antibiotics involving the ring closing metathesis of a vinyl ether
Nguyen Van, Tuyen,De Kimpe, Norbert
, p. 3443 - 3446 (2004)
The synthesis of two antibiotic pyranonaphthoquinones was performed by a straightforward synthetic route utilizing ring closing metathesis. Vinylation of 3-(1-propenyl)-2-hydroxymethyl-1,4-dimethoxynaphthalene under iridium catalysis and subsequent ring closing metathesis of 3-(1-propenyl)-2-vinyloxymethyl-1,4- dimethoxynaphthalene with Grubbs' catalyst paved the way to the natural antibiotics pentalongin and psychorubrin.
