110338-60-8

Upstream product

• 69596-94-7 dl-trans-5-bromo-6-hydroxy-1,3-dimethyl-5,6-dihydrothymine 
• 110338-60-8 (5S,6R)-6-Ethylamino-5-hydroxy-1,3,5-trimethyl-dihydro-pyrimidine-2,4-dione 
• 75-04-7 ethylamine 

Downstream Products

• 110338-60-8 (5S,6S)-6-Ethylamino-5-hydroxy-1,3,5-trimethyl-dihydro-pyrimidine-2,4-dione 

Relevant academic research and scientific papers

Stereo-Structures of Reaction Products of dl-1,3-Dimethylthymine Epoxide with Amines and L-Amino Acid Ethyl Esters

Reaction of dl-1,3-dimethylthymine epoxide (1) with amines (EtNH2, tryptamine, β-Ala-OEt, benzylamine, Gly-OEt, morpholine, neopentylamine, and aniline) afforded cis and trans adducts (2 and 3).Reaction of 1 with L-amino acid derivatives (PrO-OEt, Met-OEt

STEREOCHEMISTRY OF REACTION PRODUCTS OF 1,3-DIMETHYLTHYMINE EPOXIDE WITH AMINES

Reaction of 1,3-dimethylthymine epoxide with amines afforded cis and trans adducts, stereostructures of which were elucidated and treatment of trans adduct with borontrifluoride etherate afforded cis adduct; mechanism for the isomerization is presented.