110339-52-1Relevant articles and documents
Expeditious one-pot, four-step preparation of 2-t-butoxycarbonyl-6-hydroxy- 1,2,3,4-tetrahydroisoquinoline and an improved conversion to its 6-cyano derivative
Gordon, David W.,Bains, Carol A.
, p. 1399 - 1404 (2010)
3-Methoxy-phenethylamine was subjected to a sequential imination/Pictet- Spengler/demethylation/Boc protection sequence that allowed a one-pot preparation of N-Boc-6-hydroxy-1,2,3,4-tetrahydroisoquinoline 1. This intermediate was elaborated almost quantit
5-HT7 receptor antagonists
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Page/Page column 13, (2008/06/13)
The invention relates to compounds having pharmacological activity towards the 5-HT7 receptor, and more particularly to some tetrahydroisoquinoline substituted sulfonamide compounds of the formula I: to processes of preparation of such compounds, to pharm