110397-70-1

Upstream product

• 104-53-0 3-phenyl-propionaldehyde 
• 1514-82-5 2-bromo-3,3,3-trifluoropropene 
• 110383-07-8 O-acetyl-5-phenyl-2-(trifluoromethyl)pent-1-en-3-ol 

Downstream Products

• 110383-01-2 (Z)-7-Phenyl-4-trifluoromethyl-hept-4-enoic acid ethyl ester 
• 110383-07-8 O-acetyl-5-phenyl-2-(trifluoromethyl)pent-1-en-3-ol 
• 1401112-49-9 2-fluoro-6-((5-phenyl-2-(trifluoromethyl)pent-1-en-3-yl)oxy)pyridine 
• 1401112-06-8 2-(6-phenyl-3-(trifluoromethyl)hex-3-en-1-yl)isoindoline-1,3-dione 
• 1401112-07-9 C₂₁H₁₈F₃NO₂ 
• 160290-12-0 (E)-5-phenyl-2-(trifluoromethyl)pent-2-en-1-ol 

Relevant academic research and scientific papers

A facile access for multisubstituted trifluoromethyl olefins by visible light catalysis

Induced by visible light, a green approach for the highly substituted trifluoromethyl olefins has been developed by using alkyl boronic acid as a carbon radical precursor and the Boc-modified trifluoromethylated Baylis-Hillman adduct (BMTBHA) as an accept

Rapid and slow generation of 1-trifluoromethylvinyllithium: syntheses and applications of CF3-containing allylic alcohols, allylic amines, and vinyl ketones

1-(Trifluoromethyl)vinylation is accomplished in two protocols by the in situ generation of thermally unstable 3,3,3-trifluoroprop-1-en-2-yllithium (1):1) a rapid lithium-halogen-exchange reaction of 2-bromo-3,3,3-trifluoroprop- 1-ene (2) takes effect wit

A facile synthesis of N-[2-(trifluoromethyl)allyl]amides and their transformation into angularly trifluoromethylated bicyclic cyclopentenones

On treatment with sec-BuLi at -105°C, 2-bromo-3,3,3-trifluoropropene undergoes rapid lithium-halogen exchange to generate thermally unstable 1-(trifluoromethyl)vinyllithium, which reacts with W-tosylimines to afford N-[2-(trifluoromethyl)allyl] amides in high yield. Propargylation of the amides, followed by the Pauson-Khand reaction, readily provides pyrrolidine ring-fused cyclopentenones with an angular trifluoromethyl group. Copyright

Preparation of optically active 2-(trifluoromethyl)alkan-1-ols by catalytic asymmetric hydrogenation

The hydrogenation of (E)-2-(trifluoromethyl)alk-2-en-1-ols catalyzed by Ru-BINAP and Rh-BINAP has been carried out with good enantiomeric excess (71percent-83percent ee).Ru-BINAP-catalyzed hydrogenation converted 2-trifluoromethylacrylic acid to the corresponding saturated acid, the esterification and reduction of which gave optically active 2-(trifluoromethyl)propan-1-ol in 80percent ee.