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110406-97-8

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110406-97-8 Usage

Chemical Properties

Yellow Oil

Uses

3-(3,4-Dimethoxyphenyl)-1-chloropropane (cas# 110406-97-8) is a compound useful in organic synthesis.

Check Digit Verification of cas no

The CAS Registry Mumber 110406-97-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,0,4,0 and 6 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 110406-97:
(8*1)+(7*1)+(6*0)+(5*4)+(4*0)+(3*6)+(2*9)+(1*7)=78
78 % 10 = 8
So 110406-97-8 is a valid CAS Registry Number.

110406-97-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-(3,4-Dimethoxyphenyl)-1-chloropropane

1.2 Other means of identification

Product number -
Other names 4-(3-chloropropyl)-1,2-dimethoxybenzene

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:110406-97-8 SDS

110406-97-8Relevant articles and documents

EC18 as a Tool to Understand the Role of HCN4 Channels in Mediating Hyperpolarization-Activated Current in Tissues

Romanelli, Maria Novella,Del Lungo, Martina,Guandalini, Luca,Zobeiri, Mehrnoush,Gy?keres, András,árpádffy-Lovas, Tamás,Koncz, Istvan,Sartiani, Laura,Bartolucci, Gianluca,Dei, Silvia,Manetti, Dina,Teodori, Elisabetta,Budde, Thomas,Cerbai, Elisabetta

, p. 584 - 589 (2019)

Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are membrane proteins encoded by four genes (HCN1-4) and widely distributed in the central and peripheral nervous system and in the heart. HCN channels are involved in several physiological functions, including the generation of rhythmic activity, and are considered important drug targets if compounds with isoform selectivity are developed. At present, however, few compounds are known, which are able to discriminate among HCN channel isoforms. The inclusion of the three-methylene chain of zatebradine into a cyclohexane ring gave a compound (3a) showing a 5-fold preference for HCN4 channels, and ability to selectively modulate Ih in different tissues. Compound 3a has been tested for its ability to reduce Ih and to interact with other ion channels in the heart and the central nervous system. Its preference for HCN4 channels makes this compound useful to elucidate the contribution of this isoform in the physiological and pathological processes involving hyperpolarization-activated current.

High hypolipidemic activity of saturated side-chain α-asarone analogs

Cruz, Adriana,Garduno, Leticia,Salazar, Maria,Martinez, Elizdath,Diaz, Francisco,Chamorro, German,Tamariz, Joaquin

, p. 587 - 595 (2007/10/03)

With the aim of evaluating the pharmacophore potential of the side chain of α-asarone (1) regarding its high hypolipidemic activity, the series of derivatives 7a-7e, and 11-13 were evaluated pharmacologically. For the hydrocarbon compounds 7a-7e, with a variable-size side chain, significant decreases in serum cholesterol, LDL-cholesterol, and triglyceride levels and significant increases in HDL-cholesterol levels were observed in mice. The small-size side-chain derivatives were even more active than 1 in reducing cholesterol. The results suggested that the length and saturated character of the side chain seem to be a key feature in improving hypolipidemic activity of α-asarone (1) analogs.

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