110418-33-2Relevant academic research and scientific papers
Enantiomerically Pure 2-(Carbamoyloxy)oxiranes and Their Utility in the Synthesis od D- and L-3,6-Dideoxy-3-C-methylhexofuranosides via the Homoaldol Reaction
Hoppe, Dieter,Tarara, Gerhard,Wilckens, Marcus
, p. 83 - 88 (2007/10/02)
As an example of a novel flexible strategy in the rapid enantioselective construction of branched carbohydrate analogues by the homoaldol reaction, the title compounds were synthesized. α-Metalated (E)-2-butenyl N,N-diisopropylcarbamate is added to (S)- or (R)-2-benzyloxypropanal.The homoaldol adducts are epoxidized; methanolysis affords furanosides of branched 3,6-dideoxyaldohexoses, or, hydrolysis yields the furanoses.
