110423-27-3Relevant academic research and scientific papers
Rh(III)-Catalyzed C-H Amidation of 2-Arylindoles with Dioxazolones: A Route to Indolo[1,2-c]quinazolines
Wang, Xiaogang,Zhang, Jin,Chen, Di,Wang, Bo,Yang, Xiufang,Ma, Yangmin,Szostak, Michal
supporting information, p. 7038 - 7043 (2019/09/30)
Rhodium(III)-catalyzed C-H amidation of 2-arylindoles with dioxazolones for the synthesis of indolo[1,2-c]quinazolines is reported. The reaction is compatible with a wide range of electronically diverse 2-arylindoles and dioxazolones, providing indolo[1,2
Selective C?H or N?H Imidoylative Annulation of 2-(2-Isocyanophenyl)-1H-indoles Leading to Diverse Indole-fused Scaffolds
Teng, Fan,Hu, Weiming,Hu, Huaanzi,Luo, Shuang,Zhu, Qiang
, (2019/02/07)
2-(2-Isocyanophenyl)-1H-indoles, a class of functionalized isocyanides containing both aromatic C?H and indolo N?H functionalities, are first applied in selective imidoylative annulation reactions. Scaffolds of 6-aryl 11H-indolo[3,2-c]quinoline and 6-aryl
Selective CH or NH Imidoylative Annulation of 2-(2-Isocyanophenyl)-1H-indoles Leading to Diverse Indole-fused Scaffolds
Teng, Fan,Hu, Weiming,Hu, Huaanzi,Luo, Shuang,Zhu, Qiang
, p. 1414 - 1418 (2019/10/28)
2-(2-Isocyanophenyl)-1H-indoles, a class of functionalized isocyanides containing both aromatic CH and indolo NH functionalities, are first applied in selective imidoylative annulation reactions. Scaffolds of 6-aryl 11H-indolo[3,2-c]quinoline and 6-aryl i
Solvent-dependent copper-catalyzed indolyl C3-oxygenation and N1-cyclization reactions: Selective synthesis of 3 H-indol-3-ones and indolo[1,2- c] quinazolines
Guo, Shenghai,Wang, Fang,Tao, Li,Zhang, Xinying,Fan, Xuesen
, p. 3889 - 3896 (2018/04/14)
A simple and practical procedure for the selective preparation of 3H-indol-3-one and indolo[1,2-c]quinazoline derivatives through copper-catalyzed aerobic oxygenation and intramolecular cyclization reactions of 2-(2-amidoaryl)-1H-indoles in the presence o
Method for synthesizing indole[1,2-c]quinazoline compounds
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Paragraph 0011; 0012; 0013, (2018/09/08)
The invention discloses a method for synthesizing indole[1,2-c]quinazoline compounds, and belongs to the technical field of organic synthesis. The technical scheme of the invention is that the methodfor synthesizing the indole[1,2-c]quinazoline compounds
Regioselective Synthesis of Indolo[1,2-c]quinazolines and 11H-Indolo[3,2-c]quinolines via Copper-Catalyzed Cascade Reactions of 2-(2-Bromoaryl)-1H-indoles with Aldehydes and Aqueous Ammonia
Guo, Shenghai,Tao, Li,Zhang, Wenwen,Zhang, Xinying,Fan, Xuesen
, p. 10955 - 10964 (2015/11/18)
Highly selective and convenient synthesis of indolo[1,2-c]quinazolines and 11H-indolo[3,2-c]quinolines through copper-catalyzed one-pot cascade reactions of 2-(2-bromoaryl)-1H-indoles with aldehydes and aqueous ammonia has been achieved. Notably, the regioselectivity was easily controlled by tuning the reaction conditions. Compared with literature methods, the present protocol features easily controlled selectivity, readily available starting materials, good functional group tolerance, and simple operation procedures.
General and efficient copper-catalyzed aerobic oxidative synthesis of N-fused heterocycles using amino acids as the nitrogen source
Liu, Qing,Yang, Haijun,Jiang, Yuyang,Zhao, Yufen,Fu, Hua
, p. 15636 - 15644 (2013/09/12)
A general and efficient copper-catalyzed aerobic oxidative method for the synthesis of N-fused heterocycles has been developed by using readily available α-amino acids as the nitrogen source. The reactions underwent N-arylation, aerobic oxidative dehydrogenation, intramolecular cyclization and dissociation of formic acid. This method should provide a general and practical strategy for the construction of N-fused heterocycles.
Assembly of indolo[1,2-c]quinazolines using ZnBr2-promoted domino hydroamination-cyclization
Xu, Min,Xu, Ke,Wang, Shaozhong,Yao, Zhu-Jun
supporting information, p. 4675 - 4678 (2013/08/23)
An efficient protocol to generate indolo[1,2-c]quinazolines from acyclic alkyne substrates by ZnBr2-promoted domino hydroamination-cyclization has been established. The dichotomous properties of zinc salts involving alkynophilicity and oxophili
Copper-catalyzed cascade synthesis of 1H-indolo[1,2-c]quinazoline derivatives
Zhang, Hao,Jin, Yibao,Liu, Hongxia,Jiang, Yuyang,Fu, Hua
, p. 6798 - 6803 (2013/01/15)
A simple, efficient and practical approach to 1H-indolo[1,2-c]quinazoline derivatives has been developed that uses inexpensive and readily-available catalyst and substrates. The method should provide a new strategy for N-fused heterocycles and will show wide application in organic chemistry and medicinal chemistry. A simple, efficient and practical approach to 1H-indolo[1,2-c] quinazoline derivatives has been developed that uses inexpensive and readily-available catalyst and substrates. The method should provide a new strategy for N-fused heterocycles and will show wide application in organic chemistry and medicinal chemistry. Copyright
