110466-18-7

Upstream product

• 1569-69-3 Cyclohexanethiol 
• 100-52-7 benzaldehyde 
• 63935-93-3 benzoyltriethylsilane 
• 132868-67-8 (tert-butyldimethylsilyl)(phenyl)methanone 
• 123290-13-1 phenyltriisopropylsilylmethanone 
• 106-54-7 p-Chlorothiophenol 

Relevant academic research and scientific papers

Neutral lithium triflate (LiOTf) efficiently catalyzes chemoselective preparations of cyclic and acyclic dithioacetals from carbonyl compounds, acylals, and O,O-cyclic and open-chain acetals under solvent-free conditions

An efficient and chemoselective preparation of cyclic and acyclic thioacetals from carbonyl compounds, cyclic and acyclic acetals and acylals in the presence of catalytic amounts of neutral lithium triflate and thiols under solvent-free conditions is described.

Direct Synthesis of Unsymmetrical Dithioacetals

Dithioacetals are a frequently used motif in synthetic organic chemistry and have recently seen increasing attention as structural motif in promising antiviral agents against plant pathogens. Most existing reports, however, only discuss symmetrical dithioacetals. Examples of mixed dithioacetals are scarce and no general method for the selective synthesis of these compounds exists. Herein, a synthetically simple general one-step protocol was developed for the synthesis of a broad range of unsymmetrical dithioacetals consisting of one aromatic and one aliphatic thiol moiety from the corresponding aldehyde/thiol mixture. The mixed S,S-acetals were obtained in high yields, and a great variety of functional groups was tolerated. Kinetic control enabled an excellent selectivity in regard to the unsymmetrical dithioacetal.

Visible-Light Photoredox-Catalyzed Thioacetalization of Aldehydes Under Metal-Free and Solvent-Free Conditions

A first visible-light photoredox-catalyzed thioacetalization of aldehydes under metal-free and solvent-free conditions is described. Under blue LED irradiation, a reactive thiyl radical was initially generated through single-electron oxidation of thiol, w

Silicon benzoyl a method for preparing benzaldehyde thio-acetal

The invention provides a method for preparing benzaldehyde sulfo-acetal through benzaldehyde silicon, and relates to the field of preparation of sulfur compounds and silicon compounds. The benzaldehyde silicon and alkyl sulfhydryl (including primary merca

Lithium bromide-catalyzed highly chemoselective and efficient dithioacetalization of α,β-unsaturated and aromatic aldehydes under solvent-free conditions

Chemoselective dithioacetalization of aromatic- and α,β- unsaturated aldehydes in the presence of other structurally different aldehydes and ketones was achieved efficiently in the presence of catalytic amounts of LiBr under solvent-free conditions. Due to the neutral reaction conditions, this method is compatible with acid sensitive substrates.

Lithium trifluoromethanesulfonate (LiOTf) as a highly efficient catalyst for chemoselective dithioacetalization of carbonyl compounds under neutral and solvent-free conditions

Various types of carbonyl compound can be efficiently and chemoselectively converted to their corresponding dithioacetals in the presence of catalytic amounts of lithium triflate under solvent-free conditions. Due to the neutrality of the reaction medium, this method is especially useful for acid sensitive substrates.

Synthesis of Dithioacetals from Carbonyl Compounds and Thiols in the Presence of Polyphosphoric Acid Trimethylsilyl Ester (PPSE)

Dithioacetals were synthesized from carbonyl compounds and thiols in the presence of polyphosphoric acid trimethylsilyl ester (PPSE).Aldehydes, ketones, and trioxane could be used as carbonyl compounds, and aromatic, primary, secondary, and tertiary thiols were applicable in the present reaction.The reaction between cyclohexanone and t-butyl thiol afforded a mixture of corresponding dithioacetal and t-butylcyclohexenylsulfide.