1104732-64-0

Upstream product

• 300-57-2 allylbenzene 
• 31378-03-7 1-phenyl-2-tosylethanone 
• 4392-24-9 Cinnamyl bromide 
• 70-11-1 α-bromoacetophenone 
• 824-79-3 sodium 4-methylbenzenesulfinate 
• 140156-00-9 1-methyl-4-(2-phenylallyl)benzene 
• 4392-24-9 3-bromo-1-phenyl-1-propenyl bromide 
• 948-97-0 2,3-diphenyl-1-propene 
• 1433269-77-2 methyl 4-(2-phenylallyl)benzoate 
• 93273-60-0 1-methoxy-3-(2-phenylallyl)benzene 
• 1231245-70-7 C₁₅H₁₃Cl 
• 86148-32-5 2-phenyl-2-propen-1-ol benzoate 
• 56865-72-6 2-Phenyl-3-(phenylamino)-1-propene 

Relevant academic research and scientific papers

Copper-Catalyzed Aerobic Oxidative Cleavage of Unstrained Carbon-Carbon Bonds of 1,1-Disubstituted Alkenes with Sulfonyl Hydrazides

Alkoxy radical-mediated carbon-carbon bond cleavages have emerged as a powerful strategy to complement traditional ionic-type transformations. However, carbon-carbon cleavage reaction triggered by alkoxy radical intermediate derived from the combination of alkyl radical and dioxygen, is scarce and underdeveloped. Herein, we report alkoxy radical, which was generated from alkyl radical and dioxygen, mediated selective cleavage of unstrained carbon-carbon bond for the oxysulfonylation of 1,1-disubstituted alkenes, providing facile access to a variety of valuable β-keto sulfones. Mechanistic experiments indicated alkoxy radical intermediate that underwent subsequent regioselective β-scission might be involved in the reaction and preliminary computational studies were conducted to provide a detailed explanation on the regioselectivity of the C—C bond cleavage. Notably, the strategy was successfully applied for constructing uneasily obtained architecturally intriguing molecules.

Synthesis of arylethyl (E)-styrylsulfones and arylsulfones by one-pot DIBAL-H/NaH-mediated reaction of β-ketosulfones

A facile one-pot synthetic route for preparing a series of arylethyl (E)-styrylsulfones or arylethyl arylsulfones is developed. The efficient one-pot DIBAL-H/NaH-mediated route includes reduction of α-benzyl-β- arylketosulfones and retroaldol/aldol or retro aldol reaction of the resulting intermediate. The DIBAL-H/NaH-mediated reaction mechanism has been discussed. Georg Thieme Verlag Stuttgart. New York.

Microwave-assisted manganese(III) acetate based oxidative cyclizations of alkenes with β-ketosulfones

The microwave-assisted synthesis of 5-(4-nitrophenyl)-2-phenyl-4-(phenylsulfonyl)-2,3-dihydrofuran (5a) was performed via manganese(III) acetate based oxidative cyclization of 1-(4-nitrophenyl)-2-(phenylsulfonyl)ethanone (3a) with vinylbenzene (4a). This