1374016-46-2Relevant academic research and scientific papers
Copper Promoted Regio- and Stereoselective Aminochlorination of Alkynes and Alkenes with NFSI
Wang, Weilin,Liu, Lingyan,Chang, Weixing,Li, Jing
, p. 8542 - 8547 (2018)
A simple and rapid copper-promoted aminochlorination of unactivated alkynes and alkenes with N-fluorobenzenesulfonimide (NFSI) was developed. Two series of chloroenamines and chloroamines were obtained in good to high yields. The chlorinated enamines could be obtained in a single E configuration. This reaction involved a radical process and the CuCl2 acted as the Cl source and NFSI as the N source.
Radical aminooxygenation of alkenes with N-fluoro-benzenesulfonimide (NFSI) and TEMPONa
Li, Yi,Hartmann, Marcel,Daniliuc, Constantin Gabriel,Studer, Armido
, p. 5706 - 5709 (2015)
Reaction of various alkenes with commercially available N-fluorobenzenesulfonimide (NFSI) and TEMPONa provides the corresponding aminooxygenation products in moderate to good yields. Single electron transfer from readily generated TEMPONa to NFSI allows f
Copper-catalyzed intermolecular aminocyanation and diamination of alkenes
Zhang, Hongwei,Pu, Weiya,Xiong, Tao,Li, Yan,Zhou, Xue,Sun, Kai,Liu, Qun,Zhang, Qian
, p. 2529 - 2533 (2013)
′N′ front and center: The facile construction of C-N bonds by the generation of nitrogen-centred radicals from N-fluorobenzenesulfonimide results in the aminative difuctionalization of alkenes. The first copper-catalyzed intermolecular aminocyanation of alkenes and diamination of styrenes were realized. Si-F and B-F interactions play a significant role in the reaction. Copyright
Copper-Catalyzed Decarboxylative Functionalization of Conjugated β, Γ-Unsaturated Carboxylic Acids
Zhang, Wei,Wang, Chengming,Wang, Qiu
, p. 13179 - 13185 (2020/11/17)
Copper-catalyzed decarboxylative coupling reactions of conjugated β,γ-unsaturated carboxylic acids have been achieved for allylic amination, alkylation, sulfonylation, and phosphinoylation. This approach was effective for a broad scope of amino, alkyl, su
Synergistic copper-TEMPO catalysis of intermolecular vicinal diamination of styrenes
Weng, Shiue-Shien,Hsieh, Kun-Yi,Zeng, Zih-Jian,Zhang, Jia-Wei
supporting information, p. 670 - 673 (2017/01/25)
A copper-catalyzed, 2,2,6,6-tetramethyl piperidine N-oxy radical-assisted intermolecular diamination of styrenes with N-fluorobenzenesulfonimide has been developed. The current protocol proved amenable to a diverse array of styrenes via cascade radical addition to readily afford synthetically useful aromatic vicinal diamines with exclusive diastereoselectivity.
Iodine(III)-mediated intermolecular allylic amination under metal-free conditions
Souto, Jose A.,Zian, Debora,Muniz, Kilian
supporting information; experimental part, p. 7242 - 7245 (2012/06/16)
A new approach to direct intermolecular allylic amination has been developed using metal-free conditions at room temperature. The reaction employs a hypervalent iodine(III) reagent as an oxidant and bistosylimide as a nitrogen source. A series of different allylic aminations are presented with up to a 99% yield. Mechanistic studies including isotope labeling and Hammett correlation suggest that depending on the substrate structure two different mechanisms can be operating.
