110482-96-7

Basic information

• Product Name: Ethyl 2,2-difluoropent-4-enoate
• Synonyms: Ethyl 2,2-difluoropent-4-enoate;2,2-Difluoro-4-pentenoic acid ethyl ester;Ethyl 2,2-difluoropentenoate;Ethyl 2,2-diflouro pentane-4-enoate;Ethyl 2,2-Difluoro-4-pentenoate
• CAS NO: 110482-96-7
• Molecular Formula: C₇H₁₀F₂O₂
• Molecular Weight: 164
• Mol File: 110482-96-7.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 128℃
• Flash Point: 31℃
• Appearance: /
• Density: 1.068
• Vapor Pressure: 11.1mmHg at 25°C
• Refractive Index: 1.388
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: Ethyl 2,2-difluoropent-4-enoate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl 2,2-difluoropent-4-enoate(110482-96-7)
• EPA Substance Registry System: Ethyl 2,2-difluoropent-4-enoate(110482-96-7)

Safety Data

• Hazardous Substances Data: 110482-96-7(Hazardous Substances Data)

Usage

General Description

Ethyl 2,2-difluoropent-4-enoate, also known as ethyl 2,2-difluoro-4-pentenoate, is a chemical compound with the molecular formula C6H8F2O2. It is an ester, which is a type of organic compound formed by the reaction of an alcohol and an organic acid. This particular ester is characterized by the presence of two fluorine atoms, which are attached to the carbon atoms in the molecule. It is commonly used in organic synthesis and as a building block in the production of other chemical compounds. Its low boiling point and strong odor make it useful as a solvent in some applications. Ethyl 2,2-difluoropent-4-enoate may also have potential applications in the development of pharmaceuticals and agrochemicals due to its unique chemical structure.

InChI:InChI=1/C7H10F2O2/c1-3-5-7(8,9)6(10)11-4-2/h3H,1,4-5H2,2H3

Upstream product

• 64-17-5 ethanol 
• 55039-89-9 2,2-difluoropent-4-enoic acid 
• 113991-43-8 2,2-Difluoro-pent-4-enoyl fluoride 
• 118373-18-5 trimethylsilyl 2,2-difluoro-4-pentenoate 
• 667-27-6 Ethyl bromodifluoroacetate 
• 24850-33-7 allyltributylstanane 
• 300-57-2 allylbenzene 
• 7648-30-8 ethyl 2,2-difluoro-2-iodoacetate 
• 12775-96-1 copper 
• 106-95-6 allyl bromide 

Downstream Products

• 1356335-46-0 (+)-N-allyl-(4R,5R)-2-(1,1-difluoro-3-butenyl)-4,5-dihydro-4,5-diphenylimidazole 
• 1356335-37-9 (+)-(4R,5R)-2-(1,1-difluoro-3-butenyl)-4,5-dihydro-4,5-diphenylimidazole 
• 1267593-90-7 ethyl 3-cyclopropyl-2,2-difluoropropanoate 
• 889866-61-9 5-allyl-6-(1,1-difluorobut-3-enyl)-3-(4-methoxyphenyl)pyrimidine-2,4(1H,3H)-dione 
• 889866-62-0 5-allyl-6-(1,1-difluorobut-3-enyl)-3-(4-fluorophenyl)pyrimidine-2,4(1H,3H)-dione 
• 889866-63-1 (R)-5-allyl-6-(1,1-difluorobut-3-enyl)-3-(1-phenylethyl)pyrimidine-2,4(1H,3H)-dione 
• 889866-79-9 1-allyl-6-(1,1-difluorobut-3-enyl)-3-(4-methoxyphenyl)pyrimidine-2,4(1H,3H)-dione 
• 889866-80-2 1-allyl-6-(1,1-difluorobut-3-enyl)-3-(4-fluorophenyl)pyrimidine-2,4(1H,3H)-dione 
• 889866-81-3 (R)-1-allyl-6-(1,1-difluorobut-3-enyl)-3-(1-phenylethyl)pyrimidine-2,4(1H,3H)-dione 
• 889866-56-2 5-allyl-6-(1,1-difluorobut-3-enyl)-3-phenylpyrimidine-2,4(1H,3H)-dione 
• 889866-76-6 1-allyl-6-(1,1-difluorobut-3-enyl)-3-phenylpyrimidine-2,4(1H,3H)-dione 
• 889866-55-1 6-(1,1-difluorobut-3-enyl)-3-phenyl-5-vinylpyrimidine-2,4(1H,3H)-dione 
• 889866-57-3 6-(1,1-difluorobut-3-enyl)-3-(4-methoxyphenyl)pyrimidine-2,4(1H,3H)-dione 
• 889866-59-5 (R)-6-(1,1-difluorobut-3-enyl)-3-(1-phenylethyl)pyrimidine-2,4(1H,3H)-dione 

Relevant articles and documents

Radical reaction using an organocopper reagent derived from ethyl bromodifluoroacetate

In our previous work, reaction of ethyl bromodifluoroacetate (1) in the presence of Cu powder with olefins activated by an electron-withdrawing group gave the Michael-type adducts through an anionic intermediate. The same reaction with non-activated olefi

Preparative Flow Techniques; 1. Low-Temperature Organometallic Reactions: Synthesis of Ethyl 2,2-Difluoro-4-pentenoate

A convenient preparation of the synthetically useful ethyl 2,2-difluoro-4-pentenoate using the low-temperature flow technique is described.The method is suitable for small-scale as well as for large-scale application.

Synthesis and biological evaluation of new bicyclic fluorinated uracils through ring-closing metathesis

Two families of bicyclic fluorinated uracils have been prepared starting from a gem-difluorinated unsaturated nitrile, by means of a ring-closing metathesis reaction to form the new ring, which is fused at the C-5/C-6 or N-1/C-6 positions of the uracil mo