110652-72-7

Basic information

• Product Name: porothramycin B
• Synonyms: porothramycin B;(2E)-N,N-Dimethyl-3-[[(11R,11aS)-5,10,11,11a-tetrahydro-9,11-dimethoxy-5-oxo-1H-pyrrolo[2,1-c][1,4]benzodiazepin]-2-yl]propenamide;Antibiotic BMY-28121B;BMY-28121B
• CAS NO: 110652-72-7
• Molecular Formula: C19H23 N3 O4
• Molecular Weight: 357.4
• Mol File: 110652-72-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 599.9°Cat760mmHg
• Flash Point: 316.6°C
• Appearance: /
• Density: 1.28g/cm³
• Vapor Pressure: 2.37E-14mmHg at 25°C
• Refractive Index: 1.616
• CAS DataBase Reference: porothramycin B(CAS DataBase Reference)
• NIST Chemistry Reference: porothramycin B(110652-72-7)
• EPA Substance Registry System: porothramycin B(110652-72-7)

Safety Data

• Hazardous Substances Data: 110652-72-7(Hazardous Substances Data)

Usage

InChI:InChI=1/C19H23N3O4/c1-21(2)16(23)9-8-12-10-14-18(26-4)20-17-13(19(24)22(14)11-12)6-5-7-15(17)25-3/h5-9,11,14,18,20H,10H2,1-4H3/b9-8+/t14?,18-/m1/s1

Upstream product

• 148680-24-4 {2-[(S)-4-((E)-2-Dimethylcarbamoyl-vinyl)-2-hydroxymethyl-2,3-dihydro-pyrrole-1-carbonyl]-6-methoxy-phenyl}-carbamic acid allyl ester 
• 152032-91-2 (E)-3-[(S)-5-(hydroxymethyl)-1-(3-methoxy-2-nitrobenzoyl)-4,5-dihydro-1H-pyrrol-3-yl]-N,N-dimethylacrylamide 
• 148680-23-3 Acetic acid (S)-4-((E)-2-dimethylcarbamoyl-vinyl)-1-(3-methoxy-2-nitro-benzoyl)-2,3-dihydro-1H-pyrrol-2-ylmethyl ester 
• 148680-22-2 Acetic acid (S)-4-formyl-1-(3-methoxy-2-nitro-benzoyl)-2,3-dihydro-1H-pyrrol-2-ylmethyl ester 
• 148680-21-1 Acetic acid (S)-1-(3-methoxy-2-nitro-benzoyl)-2,3-dihydro-1H-pyrrol-2-ylmethyl ester 
• 67040-46-4 (5S)-5-[(1-ethoxyethyl)oxymethyl]tetrahydro-1H-2-pyrrolone 
• 15865-57-3 2-nitro-3-methoxybenzoyl chloride 
• 67-56-1 methanol 
• 152032-92-3 (E)-3-[(S)-5-Formyl-1-(3-methoxy-2-nitro-benzoyl)-4,5-dihydro-1H-pyrrol-3-yl]-N,N-dimethyl-acrylamide 
• 110652-73-8 Porothramycin A 

Related news

Enantioselective synthesis of (+) porothramycin B (cas 110652-72-7) and its 9-Demethoxy analogue08/16/2019

(+) 9-Demethoxyporothramycin B 3a and (+) porothramycin B 3b were synthesized from (S) pyroglutamic acid through a versatile and efficient route.detailed

Relevant articles and documents

Total synthesis of (+)-porothramycin B

The first total synthesis of (+)-porothramycin B (1b is described. Our synthetic pathway can be readily applied to the synthesis of other members of the pyrrolo[1,4]benzodiazepine antibiotics.