110652-77-2

Upstream product

• 13361-64-3 trimethyl(propargyl)silane 
• 94426-72-9 2-(2-(benzyloxy)ethyl)oxirane 
• 14657-22-8 allenyltrimethylsilane 

Downstream Products

• 110652-81-8 (Z)-1-Benzyloxy-7-trimethylsilanyl-hept-5-en-3-ol 
• 110652-85-2 (E)-1-Benzyloxy-7-trimethylsilanyl-hept-5-en-3-ol 
• 110652-97-6 (4R,6R)-4-(2-Benzyloxy-ethyl)-2,2-dimethyl-6-vinyl-[1,3]dioxane 
• 868381-43-5 7-Benzyloxy-hept-1-ene-3,5-diol 
• 110652-88-5 (3R,5S)-7-Benzyloxy-hept-1-ene-3,5-diol 
• 110652-88-5 (3S,5S)-7-Benzyloxy-hept-1-ene-3,5-diol 

Relevant academic research and scientific papers

Stereoselective synthesis of syn1,3-diols

Z-allylsilanes 1 are epoxidized by V5+/TBHP with high erythro-selectivity (up to 97:3). HF- or TBAFinduced fragmentation leads to syn-l,3-diols 3. Compound 3f can be gtransformed within two steps into a key synthon for the lactone moiety of com

STEREOSELECTIVE SYNTHESIS OF FUNCTIONALIZED ERYTHRO/1,3-DIOLS

V(5+)-Catalyzed t-butylhydroperoxide epoxidation of (Z)-5-hydroxy-2-alkenylsilanes 4 exhibit good to excellent erythro selectivity.The resulting epoxides undergo fragmentation to afford 1,3-diols 8, albeit in low chemical yield.