110652-97-6

Upstream product

• 868381-43-5 7-Benzyloxy-hept-1-ene-3,5-diol 
• 77-76-9 2,2-dimethoxy-propane 
• 110652-80-7 (Z)-6-Trimethylsilanyl-hex-4-en-2-ol 
• 110652-76-1 6-Trimethylsilanyl-hex-4-yn-2-ol 
• 94426-72-9 2-(2-(benzyloxy)ethyl)oxirane 
• 42411-87-0 syn-but-1-ene-3,5-diol 
• 110652-81-8 (Z)-1-Benzyloxy-7-trimethylsilanyl-hept-5-en-3-ol 
• 110652-77-2 1-Benzyloxy-7-trimethylsilanyl-hept-5-yn-3-ol 

Relevant academic research and scientific papers

Stereoselective synthesis of syn1,3-diols

Z-allylsilanes 1 are epoxidized by V5+/TBHP with high erythro-selectivity (up to 97:3). HF- or TBAFinduced fragmentation leads to syn-l,3-diols 3. Compound 3f can be gtransformed within two steps into a key synthon for the lactone moiety of com

STEREOSELECTIVE SYNTHESIS OF FUNCTIONALIZED ERYTHRO/1,3-DIOLS

V(5+)-Catalyzed t-butylhydroperoxide epoxidation of (Z)-5-hydroxy-2-alkenylsilanes 4 exhibit good to excellent erythro selectivity.The resulting epoxides undergo fragmentation to afford 1,3-diols 8, albeit in low chemical yield.