1106973-90-3Relevant academic research and scientific papers
Diphenylphosphinoylethylidene (DPE) acetals: an alternative protective strategy in glycochemistry
Pellizzaro, Leonardo,Tatibou?t, Arnaud,Fabris, Fabrizio,Rollin, Patrick,Lucchi, Ottorino De
body text, p. 101 - 103 (2009/04/14)
Diphenylphoshinoylethyne reacts with diols under basic conditions to produce cycloacetalic phosphine oxides. The reaction appears to be general and particularly effective with carbohydrate derivatives. The 2-(diphenylphoshinoyl)ethylidene (DPE) acetals produced are stable in acidic media while they can be cleaved under reductive and/or basic conditions: base-catalyzed transacetalization is a method of choice for their mild and effective deprotection.
