110715-46-3Relevant academic research and scientific papers
(2S,5S)-1,3-Diaza-2-phospha-2-oxo-2-chloro-3-phenylbicyclo[3.3.0]octane: A novel chiral source for borane-mediated catalytic chiral reductions
Basavaiah, Deevi,Jayapal Reddy, Gone,Chandrashekar, Vanampally
, p. 1125 - 1128 (2002)
(2S,5S)-1,3-Diaza-2-phospha-2-oxo-2-chloro-3-phenylbicyclo[3.3.0]octane has been successfully employed as a chiral catalytic source for the borane mediated asymmetric reductions of prochiral α-halo ketones to provide the desired (S)-secondary alcohols in 81-91% enantiomeric purities, thus for the first time demonstrating the potential of the N-P(=O)Cl structural framework to generate a recoverable, reusable and air stable catalyst for the asymmetric reduction processes.
A study toward understanding the role of a phosphorus stereogenic center in (5S)-1,3-diaza-2-phospha-2-oxo-3-phenylbicyclo(3.3.0)octane derivatives as catalysts in the borane-mediated asymmetric reduction of prochiral ketones
Basavaiah, Deevi,Chandrashekar, Vanampally,Das, Utpal,Reddy, Gone Jayapal
, p. 3955 - 3962 (2007/10/03)
Representative diastereomeric pairs of chiral catalysts, containing the (5S)-1,3-diaza-2-phospha-2-oxo-3-phenylbicyclo(3.3.0)octane moiety, with different stereochemistry at the phosphorus stereogenic center, have been synthesized and their stereoselection in the borane-mediated asymmetric reduction of representative prochiral ketones has been described.
Optically Active Diazacyclophosphamides: Novel Efficient Reagents for the Determination of the Absolute Configuration of Amines and Alcohols
Oshikawa, Tatsuo,Yamashita, Mitsuji,Kumagai, Sadaaki,Seo, Kuniaki,Kobayashi, Junichi
, p. 435 - 436 (2007/10/02)
Various amines and alcohols are converted into the corresponding phosphamides by the action of optically active diazacyclophosphamidic chlorides and absolute configurations of amines and alcohols are readily determined by proton and phosphorus NMR of the
New Chiral Bicyclic Phosphoramides Derived from L-Glutamic Acid
Peyronel, Jean-Francois,Samuel, Odile,Fiaud, Jean-Claude
, p. 5320 - 5325 (2007/10/02)
New cyclic chiral phosphoramides derived from (7aS)-1,2,5,6,7,7a-hexahydropyrrolodiazaphosphole 3-oxide have been synthesized and isolated in 100percent diastereomeric purity from (+)-(S)-glutamic acid.The configuration at the phosphorus atom and t
