110720-19-9Relevant academic research and scientific papers
A practical total synthesis of hapalosin, a 12-membered cyclic depsipeptide with multidrug resistance-reversing activity, by employing improved segment coupling and macrolactonization
Palomo, Claudio,Oiarbide, Mikel,Garcia, Jesus M.,Gonzalez, Alberto,Pazos, Raquel,Odriozola, Jose M.,Banuelos, Patricia,Tello, Monica,Linden, Anthony
, p. 4126 - 4134 (2004)
A practical total synthesis of hapalosin, a compound with multidrug resistance-reversing activity, has been carried out using an unprecedented macrolactonization strategy. One of the features of the new approach is the straightforward and fully stereocont
