1107640-99-2Relevant academic research and scientific papers
Nickel-catalyzed cross-coupling of β-carbonyl alkenyl pivalates with arylzinc chlorides
Pan, Wen-Jing,Wang, Zhong-Xia
, p. 1029 - 1036 (2018)
The nickel-catalyzed cross-coupling reaction of β-carbonyl alkenyl pivalates with arylzinc reagents generates 3-aryl-substituted α,β-unsaturated carbonyl compounds via C-O bond cleavage. The reaction features mild reaction conditions, a wide scope of substrates, and good functional group tolerance.
Enantioselective Hydrogenation of Endocyclic Enones: the Solution to a Historical Problem?
Lang, Qiwei,Yang, Huaxin,Gu, Guoxian,Feng, Qiang,Wen, Jialin,Zhang, Xumu
supporting information, p. 933 - 936 (2021/03/03)
The enantioselective hydrogenation of endocyclic enones has been a historical problem for homogeneous catalysis. We herein report an efficient method to reduce endocyclic enones with molecular hydrogen. Catalyzed by a rhodium/Zhaophos complex, a variety of enones with five-, six- or seven-member ring were hydrogenated with high enantioselectivity (92%—99% ee). Excellent chemo- and enantioselectivity demonstrated this method was successfully applied in the enantioselective hydrogenation of citral to produce enantio-enriched citronellal.
Stereoselective preparation of polyfunctional alkenylindium(III) halides and their cross-coupling with unsaturated halides
Shen, Zhi-Liang,Knochel, Paul
, p. 7061 - 7065 (2015/05/05)
The direct insertion of indium powder to cycloalkenyl iodides in the presence of LiCl in THF allows the preparation of new highly functionalized cycloalkenylindium(III) derivatives. In addition, we discovered that, in contrast to many metal insertions to alkenyl iodides which proceed with a loss of stereochemistry, the insertion of In/LiCl to stereodefined (Z)- and (E)-styryl iodides in THF proceeded with high retention of stereochemistry. After a palladium-catalyzed cross-coupling, various polyfunctionalized (Z)- and (E)-stilbenes were obtained with high stereoselectivity.
Functionalized alkenylzinc reagents bearing carbonyl groups: Preparation by direct metal insertion and reaction with electrophiles
S?mann, Christoph,Schade, Matthias A.,Yamada, Shigeyuki,Knochel, Paul
supporting information, p. 9495 - 9499 (2013/09/23)
Highly functionalized cyclic and acyclic alkenylzinc reagents bearing functional groups such as aldehyde, keto, and ester groups were readily prepared by either direct zinc insertion in the presence of LiCl or by magnesium insertion in the presence of LiC
Selective Heck reaction of aryl bromides with cyclopent-2-en-1-one or cyclohex-2-en-1-one
Fall, Yacoub,Doucet, Henri,Santelli, Maurice
experimental part, p. 489 - 495 (2009/04/07)
The selective Heck reaction of cyclopent-2-en-1-one or cyclohex-2-en-1-one with aryl bromides gives a simple access to the corresponding 3-arylcycloalk-2-en-1-ones. The choice of the base was found to be crucial to avoid the formation of 3-arylcyclopentan
