1108205-31-7Relevant academic research and scientific papers
Convenient formal synthesis of (+)-grandisol through Lewis acid promoted enantioselective pinacolic rearrangement
Frongia, Angelo,Girard, Christian,Ollivier, Jean,Piras, Pier Paolo,Secci, Francesco
, p. 2823 - 2825 (2008)
The titanium-mediated cyclopropanation of an easily prepared chiral a-siloxylactone leads efficiently to an enantiomerically pure cyclopropanol derivative. The trimethylsilyl trifluoromethane sulfonate induced pinacol rearrangement allows high level of chirality transfer into a cyclobutanone, which is a useful intermediate in the total synthesis of (+)-grandisol. Georg Thieme Verlag Stuttgart.
