110821-07-3

Basic information

• Product Name: 2,4-DIMETHOXY-5-PYRIMIDINECARBOXYLIC ACID
• Synonyms: 2,4-DIMETHOXY-5-PYRIMIDINECARBOXYLIC ACID;2,4-Dimethoxypyrimidine-5-carboxylic acid
• CAS NO: 110821-07-3
• Molecular Formula: C₇H₈N₂O₄
• Molecular Weight: 184.15
• Mol File: 110821-07-3.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 380.2°C at 760 mmHg
• Flash Point: 183.7°C
• Appearance: /
• Density: 1.349g/cm³
• Vapor Pressure: 1.85E-06mmHg at 25°C
• Refractive Index: 1.538
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2,4-DIMETHOXY-5-PYRIMIDINECARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-DIMETHOXY-5-PYRIMIDINECARBOXYLIC ACID(110821-07-3)
• EPA Substance Registry System: 2,4-DIMETHOXY-5-PYRIMIDINECARBOXYLIC ACID(110821-07-3)

Safety Data

• Hazardous Substances Data: 110821-07-3(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Journal of the American Chemical Society, 78, p. 2136, 1956 DOI: 10.1021/ja01591a028

InChI:InChI=1/C7H8N2O4/c1-12-5-4(6(10)11)3-8-7(9-5)13-2/h3H,1-2H3,(H,10,11)

Upstream product

• 52606-02-7 2,4-dimethoxy-5-pyrimidine carboxaldehyde 
• 124-38-9 carbon dioxide 
• 62880-71-1 5-lithio-2,4-dimethoxypyrimidine 

Downstream Products

• 15400-58-5 methyl 2,4-dimethoxypyrimidine-5-carboxylate 
• 23945-44-0 2,4-dihydroxypyrimidine-5-carboxylic acid 

Relevant articles and documents

AZABICYCLO [3. 1. O] HEXYL DERIVATIVES AS MODULATORS OF DOPAMINE D3 RECEPTORS

The present invention relates to novel compounds of formula (I) or a salt thereof: wherein R1 is a 5-membered heteroaryl group, optionally fused with a 6-membered hetero or carbocycle; such 5 or 11-membered system, may be optionally substituted by 1, 2, 3 or 4 substituents selected from the group consisting of: halogen, cyano, C1-4alkyl, haloC1-4alkyl, C1-4alkoxy, C1-4alkanoyl, haloC1-4alkoxy and SF5, and n is 1 or 2; processes for their preparation, intermediates used in these processes, pharmaceutical compositions containing them and their use in therapy, as modulators of dopamine D3 receptors, e.g. to treat drug dependency, as antipsychotic agents, to treat obsessive compulsive spectrum disorders, or premature ejaculation.