1108999-75-2Relevant academic research and scientific papers
Synthesis and antimalarial activity of new 4-amino-7-chloroquinolyl amides, sulfonamides, ureas and thioureas
Ekoue-Kovi, Kekeli,Yearick, Kimberly,Iwaniuk, Daniel P.,Natarajan, Jayakumar K.,Alumasa, John,de Dios, Angel C.,Roepe, Paul D.,Wolf, Christian
experimental part, p. 270 - 283 (2011/02/28)
We report the synthesis and in vitro antimalarial activities of more than 50 7-chloro-4-aminoquinolyl-derived sulfonamides 3-8 and 11-26, ureas 19-22, thioureas 23-26, and amides 27-54. Many of the CQ analogues prepared for this study showed submicromolar
ANTIMALARIAL QUINOLINES AND METHODS OF USE THEREOF
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Page/Page column 123-124, (2009/12/28)
One aspect of the invention relates to substitute quinolines with antimalarial activity, and compositions and kits comprising at least one of them. Another aspect of the invention relates to methods for the treatment or prevention or both of malaria compr
