111097-39-3Relevant academic research and scientific papers
Visible-light-mediated benzylic sp3 C-H bond functionalization to C-Br or C-N bond
Hou, Tianyuan,Lu, Ping,Li, Pixu
supporting information, p. 2273 - 2276 (2016/05/10)
A visible-light-promoted functionalization of unactivated benzylic sp3 C-H bonds was developed. Ethylbenzene derivatives were converted to the corresponding benzyl bromides or afforded benzylamine derivatives in a one-pot manner under visible light photoredox conditions.
The Chemistry of N-Substituted Benzotriazoles. Part 14. Novel Routes to Secondary and Tertiary Amines and to N,N-Disubstituted Hydroxylamines
Katritzky, Alan R.,Yannakopoulou, Konstantina,Lue, Ping,Rasala, Danuta,Urogdi, Laszlo
, p. 225 - 233 (2007/10/02)
Tertiary amines of types R4R3CHNR1R2 (2), (R2CH2)2NR1 (10) and 11, or (R2CH2)3N (12), secondary amines of type (R2CH2)2NH (8), and N,N-disubstituted hydroxylamines of type (R2CH2)2NOH (9), are prepared in high yield by the action of Grignard reagents or sodium borohydride on easily available N,N-dialkyl-N-amines (1) or tris(benzotriazolylmethyl)amine (7), on bis(benzotriazolylmethyl)amines (3), (5), and (6), and on N,N-bis(benzotriazolylmethyl)hydroxylamine (4), respectively.
SELECTIVE CARBOPHILIC ADDITION OF ORGANOLITHIUMS TO THIOAMIDES. A NOVEL SYNTHESIS OF UNSYMMETRICAL KETONES AND α-ALKYLATED AMINES
Tominaga, Yoshinori,Kohra, Shinya,Hosomi, Akira
, p. 1529 - 1532 (2007/10/02)
Thioamides, readily available from aldehydes, sulfur and secondary amines, can be converted to unsymmetrical ketones by the carbophilic addition of organolithiums to the thiocarbonyl group.Reduction of the intermediates with lithium aluminium hydride gives α-alkylated or α-arylated amines.
