1111321-35-7

Basic information

• Product Name: rac-N-(p-tolylsulfonyl)-2-(2-methylphenyl)aziridine
• Synonyms: rac-N-(p-tolylsulfonyl)-2-(2-methylphenyl)aziridine
• CAS NO: 1111321-35-7
• Molecular Weight: 287.382
• Mol File: 1111321-35-7.mol
• Article Data: 18

Chemical Properties

• CAS DataBase Reference: rac-N-(p-tolylsulfonyl)-2-(2-methylphenyl)aziridine(CAS DataBase Reference)
• NIST Chemistry Reference: rac-N-(p-tolylsulfonyl)-2-(2-methylphenyl)aziridine(1111321-35-7)
• EPA Substance Registry System: rac-N-(p-tolylsulfonyl)-2-(2-methylphenyl)aziridine(1111321-35-7)

Safety Data

• Hazardous Substances Data: 1111321-35-7(Hazardous Substances Data)

Upstream product

• 611-15-4 1-methyl-2-vinyl-benzene 
• 55962-05-5 [N-(p-tolylsulfonyl)imino]phenyliodinane 
• 98-59-9 p-toluenesulfonyl chloride 
• 1593-60-8 p-toluenesulfonylhydroxylamine 
• 917-54-4 methyllithium 
• 343598-64-1 N-(2-methylphenyl)methylidene-4-methylbenzenesulfonamide 
• 186581-53-3 diazomethane 
• 70-55-3 toluene-4-sulfonamide 
• 127-65-1 chloroamine-T 

Downstream Products

• 1419175-24-8 2-(4-methylphenylsulfonamido)-1-o-tolylethyl 4-nitrobenzoate 
• 1605320-66-8 tetramethyl 2-(2-methylbenzoyl)propane-1,1,3,3-tetracarboxylate 

Relevant articles and documents

Stereospecific Ring Opening and Cycloisomerization of Aziridines with Propargylamines: Synthesis of Functionalized Piperazines and Tetrahydropyrazines

Stereospecific Cu-catalyzed nucleophilic ring opening of N-sulfonylaziridines with propargylamines and subsequent hydroamination afford piperazines, which leads to double-bond isomerization to furnish tetrahydropyrazines. Optically active aziridines can be cross-coupled with high enantiomeric purities (>98% ee).

Regiodivergent and Stereospecific Aziridine Opening by Copper-Catalyzed Addition of Silicon Grignard Reagents

A stereospecific ring opening of various 2-aryl-substituted aziridines with silicon Grignard reagents under copper catalysis is reported. The regiochemical outcome is governed by the steric demand of the silicon nucleophile. The LiCl introduced with the m

First Sustainable Aziridination of Olefins Using Recyclable Copper-Immobilized Magnetic Nanoparticles

The first copper-catalyzed aziridination of olefins using recyclable magnetic nanoparticles is described. Magnetic nanoparticles were modified with dopamine and used as a support to coordinate copper. The methodology was optimized with styrene as olefin a

Iron(ii)-catalyzed intermolecular aziridination of alkenes employing hydroxylamine derivatives as clean nitrene sources

The iron-catalyzed intermolecular aziridination of alkenes with hydroxylamine derivatives is described. Using simple iron(ii) sources and readily available ligands, the formal (2 + 1) cycloaddition process proved to be efficient on both styrenes and aliphatic alkenes, providing access to a wide range of aziridines. In these particularly sustainable reaction conditions, yields up to 89% could be obtained, with a catalyst loading which could be lowered to 5 mol% when the reaction was performed on large scale. Preliminary mechanistic studies suggest that both concerted and stepwise pathways are operating in this transformation. This journal is

Transition-Metal-Free Stereospecific Oxidative Annulative Coupling of Indolines with Aziridines

Tandem C-N bond formation for the oxidative annulation of indolines with aziridines is accomplished employing the combination of DDQ and NaOCl at ambient conditions. Optically active aziridine can be coupled with high enantiomeric purity (>99% ee). The substrate scope, stereocontrol with the enantioenriched substrate, and scale-up are the important practical advantages.