111141-02-7

Basic information

• Product Name: 7-(Trifluoromethyl)chroman-4-one
• Synonyms: 7-(Trifluoromethyl)chroman-4-one;2,3-Dihydro-7-(trifluoromethyl)-4H-chromen-4-one;2,3-Dihydro-7-(trifluoromethyl)-4H-1-benzopyran-4-one;7-(trifluoroMethyl)-2,3-dihydrochroMen-4-one
• CAS NO: 111141-02-7
• Molecular Formula: C₁₀H₇F₃O₂
• Molecular Weight: 216.16
• Mol File: 111141-02-7.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 283℃
• Flash Point: 121℃
• Appearance: /
• Density: 1.374
• Vapor Pressure: 0.00339mmHg at 25°C
• Refractive Index: 1.485
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 7-(Trifluoromethyl)chroman-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 7-(Trifluoromethyl)chroman-4-one(111141-02-7)
• EPA Substance Registry System: 7-(Trifluoromethyl)chroman-4-one(111141-02-7)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 111141-02-7(Hazardous Substances Data)

Usage

General Description

7-(Trifluoromethyl)chroman-4-one is a synthetic organic compound with the chemical formula C9H5F3O2. It is a derivative of chroman-4-one, and is characterized by the presence of a trifluoromethyl group (-CF3) at the 7-position of the chroman ring. 7-(Trifluoromethyl)chroman-4-one has potential applications in medicinal chemistry, as the chroman-4-one scaffold is known to possess pharmacological activities such as antitumor, antimalarial, and antioxidant properties. The trifluoromethyl group can also enhance the lipophilicity and metabolic stability of the molecule, making it a valuable tool for drug development. Additionally, the presence of fluorine atoms can also impart unique chemical and physical properties to the compound, making it attractive for further research and potential pharmaceutical applications.

InChI:InChI=1/C10H7F3O2/c11-10(12,13)6-1-2-7-8(14)3-4-15-9(7)5-6/h1-2,5H,3-4H2

Upstream product

• 98-17-9 3-Trifluoromethylphenol 
• 1140496-03-2 C₁₀H₈ClF₃O₂ 
• 111140-93-3 3-<3-(trifluoromethyl)phenoxy>propanoic acid 
• 890839-56-2 C₁₀H₆ClF₃O 
• 145485-43-4 4-(3-(trifluoromethyl)phenyl)butanoic acid 

Downstream Products

• 1313035-20-9 [1-(benzyloxycarbonyl)piperidine]-4-spiro-2'-oxacyclopropane-3;-spiro-4'-[7'-(trifluoromethyl)chromane] 
• 1313034-99-9 N-phenyl-4-[7-(trifluoromethyl)-3,4-dihydro-2H-1-benzopyran-4-yl]piperazine-1-carboxamide 
• 1313035-08-3 benzyl 4-[7-(trifluoromethyl)-2,3-dihydrochromen-4-ylidene]piperizine-1-carboxylate 
• 1140496-05-4 (S)-7-(trifluoromethyl)chroman-4-amine 
• 1213657-96-5 C₁₀H₁₀F₃NO 
• 704208-25-3 7-Trifluoromethyl-chroman-4-ylamine 

Relevant articles and documents

4H-THIENO[3,2-C]CHROMENE-BASED INHIBITORS OF NOTUM PECTINACETYLESTERASE AND METHODS OF THEIR USE

Compounds that may be used to inhibit Notum Pectinacetylesterase are described, as well as compositions comprising them, and methods of their use to treat diseases and disorders affecting bone.

HETEROCYCLIDENE-N-(ARYL)ACETAMIDE DERIVATIVE

The blow-described formula (I): [Ch. 1] a compound represented by formula (I) : (wherein k, m, n, and p each represent 0 to 2; j and q represents 0 or 1; R1 represents a halogen atom, a hydrocarbon group, a heterocyclic group, an alkoxy group,

NOVEL HETEROCYCLIDENE ACETAMIDE DERIVATIVE

A compound represented by formula (I'): (wherein m, n, and p each represent 0 to 2; q represents 0 or 1; R1 represents halogen, a hydrocarbon group, a heterocyclic group, an alkoxy group, an alkoxycarbonyl group, a sulfamoyl group, a CN group,