1111662-40-8

Upstream product

• 108717-96-0 1-benzyl-4-phenyl-1H-[1,2,3]triazole 
• 99-91-2 para-chloroacetophenone 
• 99-90-1 para-bromoacetophenone 
• 100-39-0 benzyl bromide 
• 536-74-3 phenylacetylene 
• 622-79-7 benzyl azide 

Relevant academic research and scientific papers

Direct C–H Arylation of Heteroarenes with Aryl Chlorides by Using an Abnormal N-Heterocyclic-Carbene–Palladium Catalyst

Herein, we report a versatile catalytic system for the direct C–H arylation of heteroarenes with activated aryl chloride substrates. The catalyst works successfully for a variety of heteroarenes and aryl chloride coupling partners under very low catalyst-loading conditions. We have successfully performed the direct C–H arylations of 1-methylpyrrole, 1-methylindole, furan, thiophene, furfural, and N-benzyl-1,2,3-triazole with aryl chloride partners in good yields without the use of any additives. Furthermore, we used this catalytic process to develop a one-pot synthetic protocol for the muscle relaxant dantrolene on a gram scale. Additionally, the present catalytic system can be used to perform consecutive arylations in one pot.

Cu/Pd-catalyzed, three-component click reaction of azide, alkyne, and aryl halide: One-pot strategy toward trisubstituted triazoles

A Cu/Pd-catalyzed, three-component click reaction of azide, alkyne, and aryl halide has been developed. By using this Cu/Pd transmetalation relay catalysis, a variety of 1,4,5-trisubstituted 1,2,3-triazoles were quickly assembled in one step in high yield

Copper(I) and palladium nanoparticles supported on ethylenediamine- functionalized cellulose as an efficient catalyst for the 1,3-dipolar cycloaddition/direct arylation sequence

Cu(I) and nanoparticles of Pd supported on ethylenediamine-functionalized cellulose as a novel bio-supported catalyst was synthesized and characterized. The synthesized catalyst was found to be a highly efficient heterogeneous catalyst for the synthesis o

Catalytic direct arylations in polyethylene glycol (PEG): Recyclable palladium(O) catalyst for C-H bond cleavages in the presence of air

Two protocols for ruthenium- or palladium-catalyzed direct arylations In user-friendly polyethylene glycol (PEG) were devised, which set the stage for the development of user-friendly paliadium(0)-cataiyzed C-H bond functionalizations In the presence of a

Palladium-catalyzed direct arylations of 1,2,3-triazoles with aryl chlorides using conventional heating

Generally applicable, palladium-catalyzed direct arylations of 1,2,3-triazoles with aryl chlorides were accomplished through conventional heating at reaction temperatures of 105-120°C. Thereby, intra- and intermolecular C-H bond functionalizations were achieved with a variety of differently substituted chlorides as electrophiles, bearing numerous valuable functional groups.