111275-74-2

Basic information

• Product Name: Trifluoro-methanesulfonic acid (2R,4S,5R,2'R,4'S,5'R)-2,2'-diphenyl-5'-trifluoromethanesulfonyloxy-[4,4']bi[[1,3]dioxanyl]-5-yl ester
• Synonyms: Trifluoro-methanesulfonic acid (2R,4S,5R,2'R,4'S,5'R)-2,2'-diphenyl-5'-trifluoromethanesulfonyloxy-[4,4']bi[[1,3]dioxanyl]-5-yl ester
• CAS NO: 111275-74-2
• Molecular Weight: 622.517
• Mol File: 111275-74-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Trifluoro-methanesulfonic acid (2R,4S,5R,2'R,4'S,5'R)-2,2'-diphenyl-5'-trifluoromethanesulfonyloxy-[4,4']bi[[1,3]dioxanyl]-5-yl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Trifluoro-methanesulfonic acid (2R,4S,5R,2'R,4'S,5'R)-2,2'-diphenyl-5'-trifluoromethanesulfonyloxy-[4,4']bi[[1,3]dioxanyl]-5-yl ester(111275-74-2)
• EPA Substance Registry System: Trifluoro-methanesulfonic acid (2R,4S,5R,2'R,4'S,5'R)-2,2'-diphenyl-5'-trifluoromethanesulfonyloxy-[4,4']bi[[1,3]dioxanyl]-5-yl ester(111275-74-2)

Safety Data

• Hazardous Substances Data: 111275-74-2(Hazardous Substances Data)

Upstream product

• 61490-28-6 1,3:4,6-di-O-benzylidene-D-mannitol 
• 358-23-6 trifluoromethylsulfonic anhydride 
• 28224-73-9 1,3:4,6-di-O-benzylidene-D-mannitol 
• 100-52-7 benzaldehyde 
• 69-65-8 mannitol 

Downstream Products

• 111248-47-6 2,3:4,5-di-O-benzylidene-(3R,4R)-dihydroxy-(2S,5S)-bis(hydroxymethyl)pyrrolidine 
• 111248-46-5 N-amino-1,3:4,6-di-O-benzylidene-2,5-dideoxy-2,5-imino-L-iditol 
• 105015-44-9 (2S,3R,4R,5S)-3,4-dihydroxy-2,5-bis(hydroxymethyl)pyrrolidine 
• 133378-87-7 (2R,4aS,5aS,8R,9aR,9bR)-Perhydro-5-<(1R,4S)-2-oxa-3-azabicyclo<2.2.2>oct-5-ene-3-carbonyl>-2,8-diphenyl-2H,5H,8H-bis<1.3>dioxino<5,4-b:4',5'-d>pyrrole 
• 133378-87-7 1,3:4,6-Di-O-benzylidene-2,5-dideoxy-2,5-<<(1S,4R)-2-oxa-3-azabicyclo<2.2.2>oct-5-ene-3-carbonyl>imino>-L-iditol 
• 133378-83-3 (2R,4aS,5aS,8R,9aR,9bR)-Perhydro-2,8-diphenyl-2H,5H,8H-bis<1,3>dioxino<5,4-b:4',5'-d>pyrrole-5-carbohydroxamic acid 
• 133443-76-2 (2R,4aS,5aS,8R,9aR,9bR)-Perhydro-2,8-diphenyl-2H,5H,8H-bis<1,3>dioxino<5,4-b:4',5'-d>pyrrole 
• 111248-46-5 (2R,4aS,5aS,8R,9aR,9bR)-2,8-Diphenyl-hexahydro-bis[1,3]dioxino[5,4-b;4',5'-d]pyrrol-5-ylamine 

Relevant articles and documents

Synthesis of novel, azasugar-modified anthraquinone derivatives and their cytotoxicity

A series of novel, azasugar-modified 2-monosubstituted, 2,6- and 2,7-bissubstituted anthraquinone derivatives have been synthesized by the nucleophilic substitution of N-alkylamino azasugar with mono-, bis(2-chloroacetamido)anthraquinones. Their cytotoxic activities against HeLa and MCF-7 cells were preliminarily evaluated and compound 9a with mono-azasugar pendant at 2-position showed similar activity to the control drug (Cisplatin).

Studies on the formation of a tricyclic C2-symmetric sulfide

Attempts to synthesise chiral sulfide 1 from the dimesylate precursor 5, via a cyclisation reaction using sodium sulfide in dimethyl sulfoxide, led to the unexpected formation of an unsymmetrical furan derivative 8. Studies were made into the effect of changing the leaving group, and changing the solvent of reaction. The desired compound could be synthesized in good yields from the xanthate 9 using a radical-mediated procedure.

A Short and Practical Synthesis of (2S,5S)-Bishydroxymethyl-(3R,4R)-bishydroxypyrrolidine

D-Mannitol has been converted by five sequential reactions (benzylidenation, trifluoromethanesulphonation, hydrazinolysis, hydrogenolysis, and deacetalisation) into (2S,5S)-bishydroxymethyl-(3R,Ρ)-bishydroxypyrrolidine.