1114-07-4 Usage
Uses
Used in Pharmaceutical Industry:
(3S)-rel-3-Methyl-D-aspartic acid is used as a therapeutic agent for the treatment of neurodegenerative diseases and cognitive disorders. Its ability to modulate NMDA receptor activity makes it a potential candidate for managing conditions such as Alzheimer's disease, Parkinson's disease, and other cognitive impairments.
Used in Neuroprotective Applications:
As a neuroprotective agent, (3S)-rel-3-Methyl-D-aspartic acid is utilized to protect neurons from damage or degeneration, which can be particularly beneficial in the context of acute brain injuries or chronic neurodegenerative processes.
Used in Neuroscience Research:
(3S)-rel-3-Methyl-D-aspartic acid serves as a valuable tool in neuroscience research, aiding in the understanding of synaptic transmission and memory formation. Its role as an NMDA receptor agonist allows researchers to investigate the intricate mechanisms underlying learning and memory processes, as well as the pathophysiology of various neurological conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 1114-07-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,1 and 4 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1114-07:
(6*1)+(5*1)+(4*1)+(3*4)+(2*0)+(1*7)=34
34 % 10 = 4
So 1114-07-4 is a valid CAS Registry Number.
InChI:InChI=1/C5H9NO4/c1-2(4(7)8)3(6)5(9)10/h2-3H,6H2,1H3,(H,7,8)(H,9,10)/t2-,3+/m0/s1
1114-07-4Relevant academic research and scientific papers
Indium-mediated allylation and Reformatsky reaction on glyoxylic oximes under ultrasound irradiation
Soengas, Raquel G.,Estévez, Amalia M.
experimental part, p. 916 - 920 (2012/06/04)
A novel and more convenient method for the indium-promoted allylation of glyoxylic oximes based on the use of ultrasonic waves is reported. A similar procedure was used to develop the first example reported in the literature of an indium-mediated Reformatsky reaction on oxime ethers.
Organocatalytic synthesis of β-alkylaspartates via β-lactone ring opening
Armstrong, Alan,Geldart, Stephen P.,Jenner, Chloe R.,Scutt, James N.
, p. 8091 - 8094 (2008/02/13)
(Chemical Equation Presented) Cinchona alkaloid-catalyzed reaction of ethyl glyoxylate with substituted ketenes, formed in situ, gives disubstituted β-lactones in moderate yield and high enantiomeric excess. Subsequent azide ring opening, reduction, and e
SYNTHESIS AND ABSOLUTE STEREOCHEMISTRY OF SERRICORNIN
Mori, Kenji,Nomi, Hiroko,Chuman, Tatsuji,Kohno, Masahiro,Kato, Kunio,Noguchi, Masao
, p. 3705 - 3712 (2007/10/02)
The absolute stereochemistry of serricornin (4,6-dimethyl-7-hydroxy-3-nonanone) was established as 4S, 6S, 7S by synthesizing both (4S, 6S, 7S)-isomer and its antipode.Only the natural enantiomer was bioactive.by
