111436-92-1

Upstream product

• 111436-90-9 Methyl 5(R),6(S),7(R),8(S),9(R)-6-methoxy-8,9-dihydroxy-7-<(tert-butyldimethylsilyl)oxy>-5-vinyldec-2(E)-enoate 8,9-cyclohexyl ketal 
• 111436-91-0 5,7-Bis-benzyloxymethoxy-3H-isobenzofuran-1-one 
• 144107-96-0 methyl 4-<(benzyloxy)methoxy>-6-<(5'S,6'R,7'S,8'R)-6'-<(tert-butyldimethylsilyl)oxy>-7',8'-(cyclohexylidenedioxy)-5'-methoxy-2'-oxonon-3'(E)-enyl>-2-hydroxybenzoate 
• 120264-57-5 (3,5-Bis-benzyloxymethoxy-2-bromo-phenyl)-methanol 
• 120264-55-3 3,5-Bis-benzyloxymethoxy-benzoic acid methyl ester 
• 120264-56-4 (3,5-Bis-benzyloxymethoxy-phenyl)-methanol 
• 111436-89-6 (E)-(4S,5R)-5-(tert-Butyl-dimethyl-silanyloxy)-4-methoxy-5-((2S,3R)-3-methyl-1,4-dioxa-spiro[4.5]dec-2-yl)-pent-2-enal 
• 111437-03-7 3(R),4(S),5(R),6(S),7(R)-4-Methoxy-6,7-dihydroxy-5-<(tert-butyldimethylsilyl)oxy>-3-vinyloctanal 6.7-cyclohexyl ketal 
• 124-63-0 methanesulfonyl chloride 
• 3587-60-8 Benzyloxymethyl chloride 
• 2150-44-9 1-carbomethoxy-3,5-dihydroxybenzene 

Downstream Products

• 6680-06-4 olivin 
• 111468-56-5 Methyl 3-<1'-<<2'(R),3'(S),4'(R),5'(S),6'(R)>-3'-methoxy-5',6'--2'-<(carbomethoxymethyl)-4'-<(tert-butyldimethylsilyl)oxy>heptyl>>>-1,6,8-tris<(benzyloxy)methoxy>-2-naphthoate 
• 111436-96-5 (R)-6,8,9-Tris-benzyloxymethoxy-3-[(1S,2R)-2-hydroxy-1-methoxy-2-((2R,3R)-3-methyl-1,4-dioxa-spiro[4.5]dec-2-yl)-ethyl]-3,4-dihydro-2H-anthracen-1-one 
• 111436-97-6 (R)-6,8,9-Tris-benzyloxymethoxy-3-[(S)-1-methoxy-2-((2S,3R)-3-methyl-1,4-dioxa-spiro[4.5]dec-2-yl)-2-oxo-ethyl]-3,4-dihydro-2H-anthracen-1-one 
• 111436-95-4 (R)-6,8,9-Tris-benzyloxymethoxy-3-[(1S,2R)-2-(tert-butyl-dimethyl-silanyloxy)-1-methoxy-2-((2S,3R)-3-methyl-1,4-dioxa-spiro[4.5]dec-2-yl)-ethyl]-3,4-dihydro-2H-anthracen-1-one 
• 111436-99-8 (2S,3S)-6,8,9-Tris-benzyloxymethoxy-2-(tert-butyl-dimethyl-silanyloxy)-3-[(S)-1-methoxy-2-((2S,3R)-3-methyl-1,4-dioxa-spiro[4.5]dec-2-yl)-2-oxo-ethyl]-3,4-dihydro-2H-anthracen-1-one 
• 6680-06-4 (+) Olivin 
• 111436-96-5 3-<1'-<<1'(S),2'(R),3'(S),4'(R)>-3',4'--2'-hydroxy-1'-methoxypentyl>>-6,8,9-tris<(benzyloxy)methoxy>-1,2,3,4-tetrahydro-1(2H)-anthracenone 
• 111436-97-6 3-<1'-<<1'(S),2'(R),3'(S),4'(R)>-3',4'--1'-methoxy-2'-oxopentyl>>-6,8,9-tris<(benzyloxy)methoxy>-1,2,3,4-tetrahydro-1(2H)-anthracenone 
• 111436-95-4 3-<1'-<<1'(S),2'(R),3'(S),4'(R)>-3',4'--1'-methoxy-2'-<(tert-butyldimethylsilyl)oxy>pentyl>>-6,8,9-tris<(benzyloxy)methoxy>-1,2,3,4-tetrahydro-1(2H)-anthracenone 
• 111436-94-3 Methyl 3-<1'-<<2'(R),3'(S),4'(R),5'(S),6'(R)>-3'-methoxy-5',6'--2'-(2-oxoethyl)-4'-<(tert-butyldimethylsilyl)oxy>heptyl>>-1,6,8-tris<(benzyloxy)methoxy>-2-naphthoate 
• 111437-04-8 Methyl 3-<1'-<<2'(R),3'(S),4'(R),5'(S),6'(R)>-2'-<1-(2-hydroxyethyl)>-3'-methoxy-5',6'--4'-<(tert-butyldimethylsilyl)oxy>heptyl>>-1,6,8-tris<(benzyloxy)methoxy>-2-naphthoate 
• 111436-99-8 3-<1'-<<1'(S),2'(R),3'(S),4'(R)>-3',4'--1'-methoxy-2'-oxopentyl>>-6,8,9-tris<(benzyloxy)methoxy>-1,2,3,4-tetrahydro-2-<(tert-butyldimethylsilyl)oxy>-1(2H)-anthracenone 
• 120264-60-0 6,8,9-Tris-benzyloxymethoxy-3-[(1S,2R)-2-(tert-butyl-dimethyl-silanyloxy)-1-methoxy-2-((2S,3R)-3-methyl-1,4-dioxa-spiro[4.5]dec-2-yl)-ethyl]-1-oxo-1,2,3,4-tetrahydro-anthracene-2-carboxylic acid methyl ester 

Relevant academic research and scientific papers

An Improved Synthesis of Naphthoate Precursors to Olivin

An improved synthesis of olivin synthetic intermediate 3 is described.The synthesis involves the Horner-Wadsworth-Emmons coupling of 14 and 16, the diastereoselective vinylcuprate addition to enone 20, and the condensation of isocoumarin 25 and methyl acetate.A parallel sequence starting from allyl ether 26 has provided naphthoate 35 that is suitably differentiated for glycosylation studies.

A highly stereoselective synthesis of (+)-olivin, the aglycon of olivomycin A

The first total synthesis of (+)-olivin (1), the naturally occurring enantiomer of the aglycon of olivomycin A, is described. The synthesis is highly stereoselective, featuring the reaction of (γ-methoxyallyl)boronate 21 with chiral aldehyde 17 and the ad