111452-86-9

Basic information

• Product Name: 5-(4-Methoxy-3-{3-[4-(4-nitro-benzenesulfonyl)-phenylamino]-propoxy}-benzyl)-pyrimidine-2,4-diamine
• Synonyms: 5-(4-Methoxy-3-{3-[4-(4-nitro-benzenesulfonyl)-phenylamino]-propoxy}-benzyl)-pyrimidine-2,4-diamine
• CAS NO: 111452-86-9
• Molecular Weight: 564.622
• Mol File: 111452-86-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-(4-Methoxy-3-{3-[4-(4-nitro-benzenesulfonyl)-phenylamino]-propoxy}-benzyl)-pyrimidine-2,4-diamine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4-Methoxy-3-{3-[4-(4-nitro-benzenesulfonyl)-phenylamino]-propoxy}-benzyl)-pyrimidine-2,4-diamine(111452-86-9)
• EPA Substance Registry System: 5-(4-Methoxy-3-{3-[4-(4-nitro-benzenesulfonyl)-phenylamino]-propoxy}-benzyl)-pyrimidine-2,4-diamine(111452-86-9)

Safety Data

• Hazardous Substances Data: 111452-86-9(Hazardous Substances Data)

Upstream product

• 111453-07-7 4--4'-nitrodiphenylsulphone 
• 111453-06-6 4--4'-nitrodiphenylsulphide 
• 111453-03-3 4'-nitro-4-N-tosylaminodiphenyl sulfide 
• 83166-76-1 2,4-diamino-5-(3-hydroxy-4-methoxybenzyl)-pyrimidine 
• 111453-08-8 4--4'-nitrodiphenylsulphone 

Downstream Products

• 128076-26-6 5-(3-{3-[4-(4-Amino-benzenesulfonyl)-phenylamino]-propoxy}-4-methoxy-benzyl)-pyrimidine-2,4-diamine 

Relevant articles and documents

Synthesis of new 2,4-diamino-5-benzylpyrimidines active against various bacterial species

New inhibitors of mycobacterial dihydrofolate reductase (DHFR) have been developed.These compounds show high inhibitory activities against Gram-negative and mycobacterial DHFR exceeding that for the commercially available DHFR blockers.Amongst these compo