1114547-80-6

Basic information

• Product Name: N,N'-bis(5-bromothiophen-2-ylsulfonyl)-2,4-dichlorobenzimidamide
• CAS NO: 1114547-80-6
• Molecular Weight: 639.218
• Mol File: 1114547-80-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N,N'-bis(5-bromothiophen-2-ylsulfonyl)-2,4-dichlorobenzimidamide(CAS DataBase Reference)
• NIST Chemistry Reference: N,N'-bis(5-bromothiophen-2-ylsulfonyl)-2,4-dichlorobenzimidamide(1114547-80-6)
• EPA Substance Registry System: N,N'-bis(5-bromothiophen-2-ylsulfonyl)-2,4-dichlorobenzimidamide(1114547-80-6)

Safety Data

• Hazardous Substances Data: 1114547-80-6(Hazardous Substances Data)

Upstream product

• 53595-65-6 5-bromo-thiophene-2-sulfonamide 
• 519055-62-0 2,4-dichloro-N-[(5-bromo-2-thienyl)sulfonyl]benzenecarboxamide 

Relevant articles and documents

Development of an acyl sulfonamide anti-proliferative agent, ly573636 ? na

The synthesis of 5-bromo-thiophene-2-sulfonic acid 2,4-dichlo- robenzoylamide sodium salt on multikilogram scale is described. The initial clinical supplies were made using carbonyl diimidazole to converge the two fragments. A more efficient acid chloride process has been developed, which also provides better control of impurities and color throughout the synthesis.