111474-74-9Relevant articles and documents
Enantioselective Steglich Rearrangement of Oxindole Derivatives by Easily Accessible Chiral N,N-4-(Dimethylamino)pyridine Derivatives
Mandai, Hiroki,Fujiwara, Takuma,Noda, Katsuaki,Fujii, Kazuki,Mitsudo, Koichi,Korenaga, Toshinobu,Suga, Seiji
, p. 4436 - 4439 (2015)
Chiral N,N-4-(dimethylamino)pyridine (DMAP) derivatives, which can be readily prepared by the Ugi multicomponent reaction in a one-pot manner, have been efficiently applied to the enantioselective Steglich rearrangement of oxindole derivatives to give the
The catalytic decarboxylative allylation of enol carbonates: The synthesis of enantioenriched 3-allyl-3′-aryl 2-oxindoles and the core structure of azonazine
Babu, K. Naresh,Bisai, Alakesh,Khatua, Arindam,Pal, Souvik,Roy, Avishek
supporting information, p. 127 - 131 (2021/12/29)
The catalytic asymmetric synthesis of 3-allyl-3′-aryl 2-oxindoles has been shownviathe Pd(0)-catalyzed decarboxylative allylation of allylenol carbonates. This methodology provides access to a variety of 2-oxindole substrates (5a-v) with all-carbon quater
Organocatalytic stereoselective conjugate addition of 3-substituted oxindoles with in situ generated ortho-quinone methides
Liang, Weihong,Yin, Wenhao,Wang, Tingzhong,Qiu, Fayang G.,Zhao, Junling
supporting information, p. 1742 - 1747 (2018/04/02)
A novel method for the stereoselective conjugate addition of 3-substituted oxindoles to in situ generated o-QMs was described. This process was catalyzed efficiently by a cinchonidine-derived squaramide catalyst in oil-water phase, furnishing the corresponding 3,3-disubsituted oxindole derivatives in moderate to high yields (up to 98%) with high stereoselectivities (up to 95% ee, 15.4:1 dr). The utility of this reaction was also investigated by the gram-scale synthesis and derivatization of one of the products.