111477-17-9

Usage

Uses

Used in Pharmaceutical Development:
Imidazo[1,2-a]pyridine-8-methanol is used as a pharmacological agent for its potential role in modulating serotonin receptors in the brain. This makes it a candidate for the development of new drugs aimed at treating neurological and psychiatric disorders.
Used in Neuroscience Research:
IPA-8-methanol is utilized as a research tool in neuroscience to study the effects of serotonin receptor modulation on brain function and behavior, providing insights into the underlying mechanisms of various mental health conditions.
Used in Treatment of Neurological and Psychiatric Disorders:
Imidazo[1,2-a]pyridine-8-methanol is used as a therapeutic agent for conditions such as depression, anxiety, and substance abuse disorders, due to its potential to modulate serotonin receptors, which are implicated in these conditions.
Used in Drug Discovery for Central Nervous System Targets:
IPA-8-methanol is employed in the discovery and development of new drugs targeting the central nervous system, as its effects on serotonin receptors may lead to the creation of novel treatments for a range of neurological disorders.

Upstream product

• 107-20-0 2-chloroethanal 
• 23612-57-9 (2-amino-3-pyridinyl)methanol 
• 14667-47-1 methyl 2-aminonicotinate 
• 133427-07-3 methyl 8-imidazo<1,2-a>pyridinecarboxylate 
• 13362-26-0 2-aminopyridine-3-carboxylic acid ethyl ester 
• 158020-74-7 imidazo[1,2-a]pyridine-8-carboxylic acid ethyl ester 

Downstream Products

• 1446321-39-6 2-(imidazo[1,2-a]pyridin-8-ylmethoxy)-5-methoxybenzaldehyde 
• 167883-99-0 8-(chloromethyl)-imidazol[1,2-a]pyridine 
• 372147-63-2 (Z)-ethyl α-[(triphenylphosphoranylideneamino)-β-(imidazo[1,2-a]pyridin-8-yl)]propenoate 
• 136117-74-3 8-imidazo<1,2-a>pyridinecarboxaldehyde 

Relevant academic research and scientific papers

SUBSTITUTED BENZALDEHYDE COMPOUNDS AND METHODS FOR THEIR USE IN INCREASING TISSUE OXYGENATION

Provided are substituted benzaldehydes and derivatives thereof that act as allosteric modulators of hemoglobin, methods and intermediates for their preparation, pharmaceutical compositions comprising the modulators, and methods for their use in treating disorders mediate by hemoglobin and disorders that would benefit from increased tissue oxygenation.

IMIDAZO [1, 2-A] PYRROLO [3, 2-C] PYRIDINE COMPOUNDS USEFUL AS PESTIVIRUS INHIBITORS

The present invention relates to a series of novel imidazo[1,2-α]pyrrolo[3,2-c]pyridines (or also named 6H-1,3a,6-Tri-aza-αy-indacenes) and derivatives thereof, according to formula: (I); The present invention also relates to processes for the preparation of imidazo[1,2-α]pyrrolo[3,2-c]pyridines, their use as. a, medicine, their use to treat or prevent viral infections and their use to manufacture a medicine to treat or prevent viral infections, particularly infections with viruses belonging to the family of the Flaviviridae and more preferably infections with Bovine Viral Diarrhea virus (BVDV).

BENZISOXAZOLE COMPOUND

Disclosed is a compound represented by the general formula (I) or a salt thereof: wherein any one of R1, R2 and R3 represents a group represented by the formula: -(CH2)m-NR11R12 (wherein m is 1 or 2; and R11 and R12 independently represent a hydrogen atom or a C1-6 alkyl group or may, together with a nitrogen atom to which R11 and R12 are bound, form a 4- or 5-membered cyclic group); the remaining two or R1, R2 and R3 independently represent a group represented by the formula: -(O)n-R21 (wherein n is 0 or 1; and R21 represents a hydrogen atom, a C1-6 alkyl group, a C2-6 alkenyl group, a C2-6 alkynyl group, or the like); and R4 represents a C1-6 alkyl group which may have a substituent or the like.

Heterocyclization of functionalized vinylic derivatives of imidazo[1,2-α]pyridines

Heterocyclization of functionalized vinylic derivatives of imidazo[1,2-α]pyridines was explored experimentally and theoretically using semiempirical AM1 and ab initio methods. A range of functionalized vinylic derivatives (azido, amino, and carbodiimide groups) were prepared for conversion into pyrroloazaindoles 19-22, imidazo[1,x]-; (x=5, 6, 7, 8), [2,6]-, and [2,7]naphthyridines 28-30, 35-38 by thermal reaction. In the case of vinylic groups in the 5 position, peri annulation also was observed. The experimental and theoretical data are compared and discussed.

2-[(Imidazo[1,2-a]pyridinylmethyl)sulfinyl]-1H-benzimidazoles

This invention relates to 2-[(imidazo[1,2-a]pyridinylmethyl)-sulfinyl]-1H-benzimidazoles that are useful in the treatment and prevention of ulcers.