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Carbamic acid, [(2S)-2-hydroxypropyl]-, phenylmethyl ester is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 463967-83-1 Structure
  • Basic information

    1. Product Name: Carbamic acid, [(2S)-2-hydroxypropyl]-, phenylmethyl ester
    2. Synonyms:
    3. CAS NO:463967-83-1
    4. Molecular Formula: C11H15NO3
    5. Molecular Weight: 209.245
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 463967-83-1.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: Carbamic acid, [(2S)-2-hydroxypropyl]-, phenylmethyl ester(CAS DataBase Reference)
    10. NIST Chemistry Reference: Carbamic acid, [(2S)-2-hydroxypropyl]-, phenylmethyl ester(463967-83-1)
    11. EPA Substance Registry System: Carbamic acid, [(2S)-2-hydroxypropyl]-, phenylmethyl ester(463967-83-1)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 463967-83-1(Hazardous Substances Data)

463967-83-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 463967-83-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,6,3,9,6 and 7 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 463967-83:
(8*4)+(7*6)+(6*3)+(5*9)+(4*6)+(3*7)+(2*8)+(1*3)=201
201 % 10 = 1
So 463967-83-1 is a valid CAS Registry Number.

463967-83-1Relevant articles and documents

A Straightforward Deracemization of sec-Alcohols Combining Organocatalytic Oxidation and Biocatalytic Reduction

Liardo, Elisa,Ríos-Lombardía, Nicolás,Morís, Francisco,González-Sabín, Javier,Rebolledo, Francisca

, p. 3031 - 3035 (2018/06/27)

An efficient organocatalytic oxidation of racemic secondary alcohols, mediated by sodium hypochlorite (NaOCl) and 2-azaadamantane N-oxyl (AZADO), has been conveniently coupled with a highly stereoselective bioreduction of the intermediate ketone, catalyzed by ketoreductases, in aqueous medium. The potential of this one-pot two-step deracemization process has been proven by a large set of structurally different secondary alcohols. Reactions were carried out up to 100 mm final concentration enabling the preparation of enantiopure alcohols with very high isolated yields (up to 98 %). When the protocol was applied to the stereoisomeric rac/meso mixture of diols, these were obtained with very high enantiomeric excesses and diastereomeric ratios (95 % yield, >99 % ee, >99: 1 dr).

Modular, gold-catalyzed approach to the synthesis of lead-like piperazine scaffolds

James, Thomas,Simpson, Iain,Grant, J. Andrew,Sridharan, Visuvanathar,Nelson, Adam

supporting information, p. 6094 - 6097 (2014/01/06)

Ring-opening of cyclic sulfamidates with propargylic sulfonamides yielded substrates for a gold-catalyzed cyclization to yield tetrahydropyrazines. Manipulation of the tetrahydropyrazines, by reduction or using multicomponent reactions, yielded piperazine scaffolds in which substitution of the carbon atoms was varied. Such scaffolds may have value in the synthesis of novel screening compounds with lead-like molecular properties.

Development of a supply route for the synthesis of an iNOS inhibitor: Complications of the key SN2 reaction

Rassias, Geracimos,Hermitage, Stephen A.,Sanganee, Mahesh J.,Kincey, Peter M.,Smith, Neil M.,Andrews, Ian P.,Borrett, Gary T.,Slater, Graham R.

experimental part, p. 774 - 780 (2010/04/22)

The original medicinal chemistry synthesis of an iNOS inhibitor presented several challenges that had to be overcome in order to constitute a supply route suitable for operation on a multikilo scale. The key step in the synthesis is an SN2 reac

The first synthesis of optically active 1-substituted taurines

Xu, Jiaxi,Xu, Shu,Zhang, Qihan

, p. 466 - 471 (2007/10/03)

Optically active 1-substituted taurines, a type of important sulfur analogues of naturally occurring amino acids, and their N-benzyloxycarbonyl- protected derivatives were synthesized from the corresponding optically active β-amino secondary alcohols in t

COMBINATION THERAPY WITH INHIBITORS OF INDUCIBLE NITRIC OXIDE SYNTHASE AND ALKYLATING AGENTS

-

Page/Page column 87, (2010/02/11)

A combination therapy comprising administration of a carbamoylating chemotherapeutic agent in conjunction with administration of a selective iNOS inhibitor compound is disclosed. Optionally, resection and radiation therapy are provided with the therapeutic combination. A medicament comprising a carbamoylating chemotherapeutic agent and a selective iNOS inhibitor compound together with a pharmaceutically acceptable carrier is further disclosed. A kit comprising a carbamoylating chemotherapeutic agent and a selective iNOS inhibitor compound is further disclosed.

METHODS FOR TREATMENT AND PREVENTION OF GASTROINTESTINAL CONDITIONS

-

Page/Page column 81-82, (2010/02/06)

Therapeutic methods for the prevention ad treatment of conditions and diseases of the gastrointestinal tract involving an overproduction of nitric oxide by inducible nitric oxide synthase are described, the methods including administering to a subject in need thereof a therapeutically effective amount of a selective inhibitor of inducible nitric oxide synthase (iNOS). The methods also include the use of selective inhibitors of iNOs in combination with other therapeutic agents, including antimicrobial agents and antisecretory agents.

Agents and methods for treatment of cancer

-

, (2008/06/13)

Agents and methods for chemoprevention and treatment of neoplasia are described, the agents including a selective inhibitor of inducible nitric oxide synthase and a combination of a selective inhibitor of inducible nitric oxide synthase and an inhibitor of cylcooxygenase-2 in a pharmaceutical composition. The agents and methods are used for chemoprevention and treatment of neoplasia including colorectal cancer and other cancers affecting epithelial cells throughout the body. The agents can also be used to treat the fibrosis that occurs with radiation therapy, as well as adenomatous polyps, including those with familial adenomatous polyposis (FAP).

Amidino compound and salts thereof useful as nitric oxide synthase inhibitors

-

, (2008/06/13)

The present invention relates to S-[2-[(1-Iminoethyl)amino]ethyl]-2-methyl-L-cysteine, or a pharmaceutically acceptable salt thereof.

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