111492-60-5

Basic information

• Product Name: 1-Pyrrolidinecarboxylic acid, 2-(chlorocarbonyl)-, ethyl ester, (2S)- (9CI)
• Synonyms: 1-Pyrrolidinecarboxylic acid, 2-(chlorocarbonyl)-, ethyl ester, (2S)- (9CI)
• CAS NO: 111492-60-5
• Molecular Formula: C₈H₁₂ClNO₃
• Molecular Weight: 205.63878
• Product Categories: ACIDHALIDE
• Mol File: 111492-60-5.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Pyrrolidinecarboxylic acid, 2-(chlorocarbonyl)-, ethyl ester, (2S)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Pyrrolidinecarboxylic acid, 2-(chlorocarbonyl)-, ethyl ester, (2S)- (9CI)(111492-60-5)
• EPA Substance Registry System: 1-Pyrrolidinecarboxylic acid, 2-(chlorocarbonyl)-, ethyl ester, (2S)- (9CI)(111492-60-5)

Safety Data

• Hazardous Substances Data: 111492-60-5(Hazardous Substances Data)

Upstream product

• 147-85-3 L-proline 
• 5700-74-3 (S)-N-(ethoxycarbonyl)proline 

Downstream Products

• 1420453-39-9 C₂₅H₂₀BrNO₅ 
• 1373153-95-7 C₃₈H₄₄N₂O₈ 
• 1373153-99-1 C₃₈H₄₄N₂O₈ 
• 1373153-96-8 C₃₅H₄₆N₂O₈ 
• 1373154-00-7 C₃₅H₄₆N₂O₈ 
• 1373153-98-0 C₃₈H₄₃ClN₂O₈ 
• 1373154-02-9 C₃₈H₄₃ClN₂O₈ 
• 1373153-97-9 C₃₉H₄₆N₂O₉ 
• 1373154-01-8 C₃₉H₄₆N₂O₉ 
• 106202-17-9 ethyl (S)-2-benzoylpyrrolidine-1-carboxylate 
• 145057-61-0 N-ethoxycarbonyl-L-prolyl-(1-hydroxy)-cyclohexyl diazoethane 
• 145057-71-2 (N-ethoxycarbonyl-L-prolyl)-methyl-1-ene-2-phenyl-ethyl ketone 
• 145057-79-0 2-N-ethoxycarbonyl-L-prolyl-cyclohexanone 

Relevant articles and documents

ON-DEMAND PHOSPHORAMIDITE SYNTHESIS

The invention relates to a method of synthesis of phosphoramidites by immobilization of a phosphitylation agent on a resin activated to create a charged resin, then putting in contact with the charged resin with a suitable substrate. Phosphoramidites are synthesized in a few minutes from the application of the starting materials. Thus, the process makes it possible to create specific phosphoramidites on demand when they are needed in other applications. The substrates to be applied are mainly nucleosides, thus making it possible to create nucleoside phosphoramidites for the subsequent synthesis of oligonucleotides.

Synthesis and resolution of 2,2-dimethyl-1,3-diphenyl-1,3-propanediol, a new C2-symmetric and conformationally rigid acyclic diol

Diastereomerically pure (+)- and (-)-2,2-dimethyl-1,3-diphenyl-1,3-propanediols were synthesized starting from diethyl malonate and resolved through diesters of (-)-camphanic acid and also N-carbethoxy-L-proline. The absolute configuration of the (-)-enantiomer was established by X-ray crystallography.