111598-99-3Relevant academic research and scientific papers
A facile one-pot synthesis of α-iodo-α,β-unsaturated esters
Zhang, Xingguo,Zhong, Ping,Chen, Fan
, p. 1729 - 1736 (2004)
Aldehydes reacted with (ethoxycarbonyliodomethyl)triphenylphosphonium iodide, tetrabutylammonium bromide, and potassium carbonate in methanol at 40°C to give α-iodo-α,β-unsaturated esters in good to excellent yield.
The stereospecific trifluoromethylation of α-iodo-α,β-unsaturated esters: A novel synthesis of (Z)-α-trifluoromethyl-α,β-unsaturated esters
Zhang, Xingguo,Qing, Feng-Ling,Peng, Yiyuan
, p. 79 - 82 (2007/10/03)
This paper describes simple and successful methods for the preparation of α-iodo-α,β-unsaturated esters. The trifluoromethylation of (Z)-α-iodo-α,β-unsaturated esters stereo-selectively provides (Z)-α-trifluoromethyl-α,β-unsaturated esters.
(Ethoxycarbonyliodomethyl)triphenylphosphonium Iodide: A Convenient Reagent for the Direct Synthesis of β-Substituted Propiolic Acids via the Corresponding Esters
Chenault, Jaques,Dupin, Jean-Francois E.
, p. 498 - 499 (2007/10/02)
Reaction between (ethoxycarbonyliodomethyl)triphenylphosphonium iodide, potassium carbonate, and various aromatic or aliphatic aldehydes in a liquid solid two phases system gives β-substituted propiolic esters.The corresponding acids are obtained in good yield by hydrolysis.
