1116-26-3

Basic information

• Product Name: (1E,3Z)-buta-1,3-diene-1,2,4-tricarboxylic acid
• CAS NO: 1116-26-3
• Molecular Formula: C₇H₆O₆
• Molecular Weight: 186.1189
• Mol File: 1116-26-3.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 423°C at 760 mmHg
• Flash Point: 223.8°C
• Density: 1.618g/cm³
• Vapor Pressure: 2.43E-08mmHg at 25°C
• Refractive Index: 1.596
• CAS DataBase Reference: (1E,3Z)-buta-1,3-diene-1,2,4-tricarboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (1E,3Z)-buta-1,3-diene-1,2,4-tricarboxylic acid(1116-26-3)
• EPA Substance Registry System: (1E,3Z)-buta-1,3-diene-1,2,4-tricarboxylic acid(1116-26-3)

Safety Data

• Hazardous Substances Data: 1116-26-3(Hazardous Substances Data)

Upstream product

• 99-50-3 3,4-Dihydroxybenzoic acid 
• 81158-26-1 1-methyl cis,cis-3-carboxymuconate 

Downstream Products

• 13249-46-2 γ-carboxymuconolactone 

Relevant articles and documents

In vitro reconstitution of the catabolic reactions catalyzed by PcaHG, PcaB, and PcaL: The protocatechuate branch of the β-ketoadipate pathway in Rhodococcus jostii RHA1

The β-ketoadipate pathway is a major pathway involved in the catabolism of the aromatic compounds in microbes. The recent progress in genome sequencing has led to a rapid accumulation of genes from the β-ketoadipate pathway in the available genetic database, yet the functions of these genes remain uncharacterized. In this study, the protocatechuate branch of the β-ketoadipate pathway of Rhodococcus jostii was reconstituted in vitro. Analysis of the reaction products of PcaHG, PcaB, and PcaL was achieved by high-performance liquid chromatography. These reaction products, β-ketoadipate enol-lactone, 3-carboxy-cis,cis-muconate, γ-carboxymuconolactone, muconolactone, and β-ketoadipate, were further characterized using LC-MS and nuclear magnetic resonance. In addition, the in vitro reaction of PcaL, a bidomain protein consisting of γ-carboxy-muconolactone decarboxylase and β-ketoadipate enol-lactone hydrolase activities, was demonstrated for the first time. This work provides a basis for analyzing the catalytic properties of enzymes involved in the growing number of β-ketoadipate pathways deposited in the genetic database.

IMMOBILIZATION OF PROTOCATECHUATE 3,4-DIOXYGENASE FROM PLEUROTUS OSTREATUS ON ACTIVATED POROUS GLASS BEADS

Protocatechuate 3,4-dioxygenase (protocatechuate: oxygen 3,4-oxidoreductase, EC 1.13.11.3) purified from the wood-degrading fungus Pleurotus ostreatus was immobilized on glass beads.The per cent attached protein was 78 with a retained enzymatic activity of 90percent.The basic properties of the immobilized enzyme were tested and compared with those of a soluble form.Immobilized dioxygenase was stable over wide ranges of pH and temperature.Moreover, the immobilization brought about a slight increase of its specific activity.Key Words Index - Pleurotus ostreatus; protocatechuate 3,4-dioxygenase; immobilization; porous glass beads.

The metabolism of protocatechuic acid by Neurospora.

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