1116084-90-2Relevant academic research and scientific papers
Synthesis and conformational features of 4-(cyclohexylsulfanyl)-1-(2,4- dinitrophenyl)-3-aryl-1H-pyrazole
Manikannan, Ramaiyan,Venkatesan, Ramaiyan,Muthusubramanian, Shanmugam
experimental part, p. 1916 - 1928 (2011/06/23)
A set of new 4-(cyclohexylsulfanyl)-1,3-diaryl-1H-pyrazoles has been synthesized using Vilsmeier's reagent. It is found that 4-(cyclohexylsulfanyl)- 1-(2,4-dinitrophenyl)-3-(4-methoxyphenyl)-1H-pyrazole exists with the arylthio group in the equatorial pos
Discovery and SAR of small molecule PAR1 antagonists
Rilatt, Ian,Mirabel, Etienne,Grand, Bruno Le,Perez, Michel
scheme or table, p. 903 - 906 (2010/07/20)
High-throughput screening resulted in the identification of a small molecule inhibitor of PAR1. Optimisation of the initial hit led to the discovery of compounds 34 and 49, which displayed antithrombotic activity in an arteriovenous shunt model in the rat after iv administration.
Selective one-pot multicomponent synthesis and anti-tubercular evaluation of 5-(aryl/cyclohexylsulfanyl)-2-alkoxy-4,6-diarylnicotinonitriles
Manikannan, Ramaiyan,Muthusubramanian, Shanmugam,Yogeeswari, Perumal,Sriram, Dharmarajan
supporting information; experimental part, p. 3352 - 3355 (2010/08/07)
A new set of highly substituted pyridine derivatives has been synthesized by a product selective four component reaction of aryl aldehyde, malononitrile and 2-aryl/cyclohexylsulfanyl-1-aryl-1-ethanones in presence of sodium hydroxide in methyl/ethyl alcoh
Pyrazole derivatives from azines of substituted phenacyl aryl/cyclohexyl sulfides and their antimycobacterial activity
Manikannan, Ramaiyan,Venkatesan, Ramaiyan,Muthusubramanian, Shanmugam,Yogeeswari, Perumal,Sriram, Dharmarajan
supporting information; experimental part, p. 6920 - 6924 (2011/02/22)
Azines derived from substituted phenacyl aryl/cyclohexyl sulfide on treatment with excess phosphorous oxychloride in N,N-dimethylformamide have been found to yield two isomeric pyrazoles in each case. A plausible mechanism has been suggested for the forma
Synthesis and characterization of 5-(cyclohexylsulfanyl)-4-aryl-1,2,3- selena/thiadiazoles
Saravanan, Sivaperuman,Namitharan, Kayambu,Muthusubramanian, Shanmugam
, p. 305 - 309 (2008/09/20)
The synthesis and characterization of new 5-(cyclohexyl-sulfanyl)-4-aryl-1, 2,3-selena/thiadiazoles, obtained from the α-sulfanyl semicarbazones are described. The structures of these compounds have been established by 1H NMR, 13C NM
