1116690-31-3

Basic information

• Product Name: 2-(2-bromopentyl)-4-(3,4-dimethoxyphenyl)-4a,5,6,7,8,8a-hexahydrophthalazin-1(2H)-one
• Synonyms: 2-(2-bromopentyl)-4-(3,4-dimethoxyphenyl)-4a,5,6,7,8,8a-hexahydrophthalazin-1(2H)-one
• CAS NO: 1116690-31-3
• Molecular Weight: 435.361
• Mol File: 1116690-31-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(2-bromopentyl)-4-(3,4-dimethoxyphenyl)-4a,5,6,7,8,8a-hexahydrophthalazin-1(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-bromopentyl)-4-(3,4-dimethoxyphenyl)-4a,5,6,7,8,8a-hexahydrophthalazin-1(2H)-one(1116690-31-3)
• EPA Substance Registry System: 2-(2-bromopentyl)-4-(3,4-dimethoxyphenyl)-4a,5,6,7,8,8a-hexahydrophthalazin-1(2H)-one(1116690-31-3)

Safety Data

• Hazardous Substances Data: 1116690-31-3(Hazardous Substances Data)

Upstream product

• 91-16-7 1,2-dimethoxybenzene 
• 85-42-7 1,2-Cyclohexanedicarboxylic acid-anhydride 
• 439660-78-3 2-[1-(3,4-dimethoxy-phenyl)-methanoyl]-cyclohexanecarboxylic acid 
• 439660-85-2 6-(3,4-dimethoxy-benzoyl)-cyclohex-3-enecarboxylic acid 
• 935-79-5 cis-1,2,3,6-tetrahydrophthalic anhydride 
• 89980-69-8 3,4-dimethoxyphenylmagnesium bromide 
• 111-24-0 1,5-dibromo-pentane 
• 357980-82-6 4-(3,4-dimethoxy-phenyl)-4a,5,8,8a-tetrahydro-2H-phthalazin-1-one 

Downstream Products

• 878663-15-1 C₃₇H₄₂F₃N₃O₄ 
• 878663-14-0 C₃₇H₄₂F₃N₃O₄ 

Relevant articles and documents

Design, synthesis and evaluation of dual pharmacology β2- adrenoceptor agonists and PDE4 inhibitors

A novel series of formoterol-phthalazinone hybrids were synthesised and evaluated as dual pharmacology β2-adrenoceptor agonists and PDE4 inhibitors. Most of the hybrids displayed high β2-adrenoceptor agonist and moderate PDE4 inhibitory activities. The most potent compound, (R,R)-11c, exhibited agonist (EC50 = 1.05 nM, pEC50 = 9.0) and potent PDE4B2 inhibitory activities (IC50 = 0.092 μM).