111761-70-7Relevant articles and documents
Spirocyclic Penicillins
Burton, George,Harrington, Frank P.
, p. 635 - 638 (2007/10/02)
The intramolecular, mercury-mediated cyclisation of (6S)-benzyl 6--6-(methylthio)penicillinates, (8) and (9), has been shown to give spiro derivatives.Unexpectedly, products (16) and (17), derived from attack on the more-hindered β-face, were isolated in addition to the predicted products (10) and (11), formed by attack on the α-face.Formylation and removal of the carboxy protecting group gave spirocyclic penicillins devoid of useful antibacterial activity.