35353-41-4

Usage

Uses

Used in Pharmaceutical and Organic Chemistry Research:
(R)-2-azido-2-phenylacetyl chloride is used as a reagent for the synthesis of various compounds, particularly in the development of new pharmaceuticals and materials. Its versatility and reactivity make it a valuable tool in these fields.
Used in Bioconjugation:
(R)-2-azido-2-phenylacetyl chloride is used as a bioconjugation agent to attach chemical groups to biomolecules for various research and diagnostic purposes. This application allows for the enhancement of the functionality and properties of biomolecules, making them suitable for a wide range of applications in the life sciences.

InChI:InChI=1/C8H6ClN3O/c9-8(13)7(11-12-10)6-4-2-1-3-5-6/h1-5,7H/t7-/m1/s1

Upstream product

• 29125-25-5 (R)-2-azido-2-phenylacetic acid 

Downstream Products

• 111761-71-8 (2R,3'S,5R,5'R)-benzyl 1-formyl-2',2'-dimethyl-4-oxo-5-phenylspiro-3'-carboxylate 
• 111761-71-8 (2R,3'S,5S,5'R)-benzyl 1-formyl-2',2'-dimethyl-4-oxo-5-phenylspiro-3'-carboxylate 
• 111821-11-5 (6S)-benzyl 6-<(S)-2-amino-2-phenylacetamido>-6-(methylthio)penicillanate 
• 111821-10-4 (6S)-benzyl 6-<(R)-2-amino-2-phenylacetamido>-6-(methylthio)penicillanate 
• 111761-70-7 (2R,3'S,5R,5'R)-benzyl 2',2'-dimethyl-4-oxo-5-phenylspiro-3'-carboxylate 
• 111761-70-7 (2R,3'S,5S,5'R)-benzyl 2',2'-dimethyl-4-oxo-5-phenylspiro-3'-carboxylate 
• 111761-70-7 (2S,3'S,5S,5'R)-benzyl 2',2'-dimethyl-4-oxo-5-phenylspiro-3'-carboxylate 
• 111761-70-7 (2S,3'S,5R,5'R)-benzyl 2',2'-dimethyl-4-oxo-5-phenylspiro-3'-carboxylate 
• 111761-72-9 (2R,3'S,5R,5'R)-1-formyl-2',2'-dimethyl-4-oxo-5-phenylspiro-3'-carboxylic acid 
• 111761-72-9 (2R,3'S,5S,5'R)-1-formyl-2',2'-dimethyl-4-oxo-5-phenylspiro-3'-carboxylic acid 
• 111761-69-4 (6S)-benzyl 6-<(R)-2-azido-2-phenylacetamido>-6-(methylthio)penicillanate 

Relevant academic research and scientific papers

Spirocyclic Penicillins

The intramolecular, mercury-mediated cyclisation of (6S)-benzyl 6--6-(methylthio)penicillinates, (8) and (9), has been shown to give spiro derivatives.Unexpectedly, products (16) and (17), derived from attack on the more-hindered β-face, were isolated in addition to the predicted products (10) and (11), formed by attack on the α-face.Formylation and removal of the carboxy protecting group gave spirocyclic penicillins devoid of useful antibacterial activity.