111818-57-6

Basic information

• Product Name: Benzeneacetic acid, -alpha--methyl--alpha--[(1-oxo-2-propenyl)amino]- (9CI)
• Synonyms: Benzeneacetic acid, -alpha--methyl--alpha--[(1-oxo-2-propenyl)amino]- (9CI)
• CAS NO: 111818-57-6
• Molecular Formula: C12H13NO3
• Molecular Weight: 219.24
• Mol File: 111818-57-6.mol
• Article Data: 2

Chemical Properties

• Melting Point: 172-174 °C(Solv: ethanol (64-17-5); water (7732-18-5))
• Boiling Point: 452.6±45.0 °C(Predicted)
• Appearance: /
• Density: 1.186±0.06 g/cm3(Predicted)
• PKA: 3.21±0.10(Predicted)
• CAS DataBase Reference: Benzeneacetic acid, -alpha--methyl--alpha--[(1-oxo-2-propenyl)amino]- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetic acid, -alpha--methyl--alpha--[(1-oxo-2-propenyl)amino]- (9CI)(111818-57-6)
• EPA Substance Registry System: Benzeneacetic acid, -alpha--methyl--alpha--[(1-oxo-2-propenyl)amino]- (9CI)(111818-57-6)

Safety Data

• Hazardous Substances Data: 111818-57-6(Hazardous Substances Data)

Upstream product

• 143-33-9 sodium cyanide 
• 98-86-2 acetophenone 
• 814-68-6 acryloyl chloride 

Relevant articles and documents

A ONE-POT TRANSFORMATION OF KETONES INTO N-(METH)ACRYLOYL-2-AMINO ACIDS

A synthetic sequence for the preparation of N-(meth)acryloyl-2-amino acids is outlined which involves transformation of a ketone successively into an aminonitrile and a (meth)acrylamidonitrile, followed by selective hydrolysis of the nitrile function.All reactions are performed in aqueous media, in one reaction vessel, and in a stepwise manner without isolation of any intermadiate products.